ID   GSM1_PICST              Reviewed;         520 AA.
AC   A3LWY2;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; Synonyms=HBR1; ORFNames=PICST_68007;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; CP000500; ABN67713.2; -; Genomic_DNA.
DR   RefSeq; XP_001385742.2; XM_001385705.1.
DR   AlphaFoldDB; A3LWY2; -.
DR   STRING; 322104.A3LWY2; -.
DR   EnsemblFungi; ABN67713; ABN67713; PICST_68007.
DR   GeneID; 4840334; -.
DR   KEGG; pic:PICST_68007; -.
DR   eggNOG; ENOG502R2ZP; Eukaryota.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   InParanoid; A3LWY2; -.
DR   OMA; CHEKHLQ; -.
DR   OrthoDB; 681770at2759; -.
DR   Proteomes; UP000002258; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..520
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406490"
FT   DOMAIN          376..445
FT                   /note="PAS"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   520 AA;  59472 MW;  FD562E539C5211CE CRC64;
     MTKRLSPHEK KNRKPASRAC VFCHEKHLQC SNERPCKNCV KRGLAHECRD VIRKRAKYLN
     TNSRRGSEAQ AHADYPHNPI DGFMSPTIKP EIPSPASNMV VSPQFVGNAL LQQEVQHPQQ
     FHPQQQQKLS LHNSMLNTTN DVLNRLLEEQ NFKDTDSDNM SANSVNASRP NTAIGTGTFS
     SNYLNEEYLM LGDIILHSKP TSPSPSNTSV SEYNTNTVSP NFSSQINYDD LNQPRRKVLQ
     RLKDSRPFIS LGFSNESSQL PNLNSSNIAQ SSSIPTEYVS PLVTHHLYQS VQDIYTNNIM
     NFDYPQSYHS LTHFLKKRFS GNNLPAEQKQ AKRQSLLVIL KLIASYRPTF ISAHKSLLKP
     YDLQFLEMTF QRCLIDYEKL SQLNSSPTII WRRTGEIVSI TDDLLSLLGY NLADLLSHRT
     FIMELMYDDE SITNYFRLFK TVAVGNLHSS IITKIKLTKN QNRNVSDQTG TRRLSYELSE
     RDHIEFCSVW TVKRDMFDLP MMIIGQFLPI LPAGDGVRMY