ID   GSM1_YEAS7              Reviewed;         618 AA.
AC   A6ZQM3;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Glucose starvation modulator protein 1;
GN   Name=GSM1; ORFNames=SCY_3184;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- FUNCTION: Transcription factor which regulates nonfermentable carbon
CC       utilization. Binds specifically to 5'-CGGN(8)CGG-3' and 5'-CGGN(9)CGG-
CC       3' sequences in the promoter region (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}.
CC   -!- SIMILARITY: Belongs to the ERT1/acuK family. {ECO:0000305}.
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DR   EMBL; AAFW02000044; EDN63275.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZQM3; -.
DR   EnsemblFungi; EDN63275; EDN63275; SCY_3184.
DR   HOGENOM; CLU_010748_2_2_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..618
FT                   /note="Glucose starvation modulator protein 1"
FT                   /id="PRO_0000406494"
FT   DOMAIN          466..538
FT                   /note="PAS"
FT   DNA_BIND        20..48
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT   REGION          325..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        335..352
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   618 AA;  70298 MW;  7A0786681B55EC0C CRC64;
     MTKKLPSELK QTRKSIQTAC EFCHTKHIQC DVGRPCQNCL KRNIGKFCRD KKRKSRKRIE
     KHGTQPYLNL GKRLVIHDVP SKTVSPSSVH LQRDFLSSDQ EKPGKTPAHN TNIQYTYNIN
     DNFQSAGSIP RITNFNTDNG QTVLENTSNN ISASQAVHLM NDPIIPTVRK STLNLKSHFL
     EQHKAMQQPL ATNCLVATSN VPVHSGMDTS NKSDDDVDDE TNIHFDSMWC NDEYMKLKDI
     VDISTPFLPN NSQIFSLQES EYPNPSASTR GNSSLHLTNL LNSTKSVNDQ KDSSIGHSTS
     TFNTYDEVVS RPFISLDMLH LNRGANANTH PSHNAKLESE CDSSSHSDAD LEKHDTDFIS
     PSKFRELVKT PQDLYDNKCL IKPHNYKLAY TKLLTTLRKK FLEGAEIDKS VSVKDEHSTQ
     KHNLRYDLEV IIRSILERYA PIFISLTSNM IEEDLLLQEV TLQRALLDLE NMAKLVSCTP
     MCIWRRSGEI CFVSNEFYSL TGFNKNLLLD RTSFIFEYLD HKSVSNYFQI FNELLAFGYN
     DINKRKKLLM LNACSSTSSK ITEGFSFTTD GKAIFTKCNL LLSNGLYLKC ACCWTVKRDS
     FNIPILVMGQ FLPIFEMD