ID   GSPC_AERHY              Reviewed;         290 AA.
AC   P45790;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Type II secretion system protein C;
DE            Short=T2SS protein C;
DE   AltName: Full=General secretion pathway protein C;
GN   Name=exeC;
OS   Aeromonas hydrophila.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=644;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ah65;
RA   Howard S.P.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in a type II secretion system (T2SS, formerly
CC       general secretion pathway, GSP) for the export of proteins.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GSP C family. {ECO:0000305}.
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DR   EMBL; X66504; CAA47125.1; -; Genomic_DNA.
DR   AlphaFoldDB; P45790; -.
DR   SMR; P45790; -.
DR   STRING; 1448139.AI20_16535; -.
DR   eggNOG; COG3031; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR   GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR024961; T2SS_GspC_N.
DR   InterPro; IPR001639; T2SS_protein-GspC.
DR   Pfam; PF11356; T2SSC; 1.
DR   PRINTS; PR00810; BCTERIALGSPC.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   TIGRFAMs; TIGR01713; typeII_sec_gspC; 1.
DR   PROSITE; PS01141; T2SP_C; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..290
FT                   /note="Type II secretion system protein C"
FT                   /id="PRO_0000214998"
FT   TOPO_DOM        1..28
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        29..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..290
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  31363 MW;  9D87BDDD660DABC7 CRC64;
     MTLPFRNDLL SSLLARCKTV PLSRFSQPLF WLLLLLLAHQ CAGLTWRLLD LGSQQASQPW
     QPAMVASQGQ GSARLDLSGI SRLSLFGKAK QQAQAADAVA ADAPKTQLNA QLNGVLASSD
     PAKSIAIIAH NGVQNSYGIG DFIDGTQAKI RQVFADRVII ERDGRDETLM LDGEEYGKPL
     PKPGNQDDKL SSVRSELLGN PGKITDYLNI SPVRVDGRMV GYRLNPGSNP ELFNQLGLVA
     NDMAVSINGL DLRDNAQAMQ AMQQVAGATE MTVTVERQGQ LYDVYVGLSE