ID   GSPC_AERSA              Reviewed;         290 AA.
AC   P45772;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Type II secretion system protein C;
DE            Short=T2SS protein C;
DE   AltName: Full=General secretion pathway protein C;
GN   Name=exeC;
OS   Aeromonas salmonicida.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=645;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33658 / DSM 19634 / JCM 7874 / NCIMB 1102 / NCTC 12959;
RX   PubMed=7789814; DOI=10.1016/0378-1119(95)00139-w;
RA   Karlyshev A.V., Macintyre S.;
RT   "Cloning and study of the genetic organization of the exe gene cluster of
RT   Aeromonas salmonicida.";
RL   Gene 158:77-82(1995).
CC   -!- FUNCTION: Involved in a type II secretion system (T2SS, formerly
CC       general secretion pathway, GSP) for the export of proteins.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GSP C family. {ECO:0000305}.
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DR   EMBL; X80505; CAA56667.1; -; Genomic_DNA.
DR   PIR; I39677; S46962.
DR   AlphaFoldDB; P45772; -.
DR   SMR; P45772; -.
DR   STRING; 1233098.GCA_000315855_00771; -.
DR   OMA; WRIIPEP; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR   GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR024961; T2SS_GspC_N.
DR   InterPro; IPR001639; T2SS_protein-GspC.
DR   Pfam; PF11356; T2SSC; 1.
DR   PRINTS; PR00810; BCTERIALGSPC.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   TIGRFAMs; TIGR01713; typeII_sec_gspC; 1.
DR   PROSITE; PS01141; T2SP_C; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..290
FT                   /note="Type II secretion system protein C"
FT                   /id="PRO_0000214999"
FT   TOPO_DOM        1..28
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        29..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..290
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  31302 MW;  DB102F3E365A90FE CRC64;
     MTLPFRDDLL SSLLARCKTV PLSRFSQPLF WLLLLLLAHQ CAGLTWRLLD LGSQQSSQPW
     QPAVAGSQGQ GKARLDLGGV SRLALFGKAK QQARAADAVA ADAPKTQLNA QLNGVLASSD
     PAKSIAIIAH SGVQNSYGIG DFIDGTQAKV RQVFADRVII ERDARDETLM LDGEEYGKPL
     PKQGNPDEKL SSVRSELLGN PGKITDYLNI SPVRVDGRMV GYRLNPGSNP ELFNQLGLVA
     NDMAVSINGL DLRDNAQAMQ AMQQVAGATE MTVTVERQGQ LYDVYVGLSE