ID   GSPC_KLEPN              Reviewed;         285 AA.
AC   P15643;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Type II secretion system protein C;
DE            Short=T2SS protein C;
DE   AltName: Full=General secretion pathway protein C;
DE   AltName: Full=Pullulanase secretion envelope PulC;
GN   Name=pulC; Synonyms=malX;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2677007; DOI=10.1016/s0021-9258(18)71517-2;
RA   D'Enfert C., Reyss I., Wandersman C., Pugsley A.P.;
RT   "Protein secretion by Gram-negative bacteria. Characterization of two
RT   membrane proteins required for pullulanase secretion by Escherichia coli K-
RT   12.";
RL   J. Biol. Chem. 264:17462-17468(1989).
CC   -!- FUNCTION: Involved in a type II secretion system (T2SS, formerly
CC       general secretion pathway, GSP) for the export of proteins. Required
CC       for the translocation of pullulanase.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Single-pass membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the GSP C family. {ECO:0000305}.
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DR   EMBL; M32613; AAA25125.1; -; Genomic_DNA.
DR   PIR; A34469; A34469.
DR   AlphaFoldDB; P15643; -.
DR   SMR; P15643; -.
DR   TCDB; 3.A.15.1.1; the outer membrane protein secreting main terminal branch (mtb) family.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR   GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProt.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR024961; T2SS_GspC_N.
DR   InterPro; IPR001639; T2SS_protein-GspC.
DR   Pfam; PF11356; T2SSC; 1.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   TIGRFAMs; TIGR01713; typeII_sec_gspC; 1.
DR   PROSITE; PS01141; T2SP_C; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..285
FT                   /note="Type II secretion system protein C"
FT                   /id="PRO_0000215004"
FT   TOPO_DOM        1..27
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47..285
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   285 AA;  30999 MW;  06A4C295978E9EF9 CRC64;
     MSKGIKMHNS VMRLTIPNKK IINYAPHIVT SIILFFICQQ LAQLTWKIIL PVNFTDNALS
     SADMTSPAAP SAETALPRFT LFGLAEKTSA SAPGGNLDQA PVSALRLRVT GLLASTDPSR
     AIAIMMKGNQ QVSLGIGDNT PGGEAKIIAI SPDRLIVNYR GRNEAIPLFN DPPAVGKNSA
     APPARHLAQE LRAQPQNILH YLNISPVMVN DKLSGYRLNP GKDPALFRQS GLRENDLAIA
     LNGLDLRDKE QARQVLAQLP ELTEITLTVE RDGQKNDIYL ALRDE