ID   GSPK_XANCP              Reviewed;         283 AA.
AC   P34026;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2002, sequence version 3.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Type II secretion system protein K;
DE            Short=T2SS protein K;
DE   AltName: Full=General secretion pathway protein K;
DE   Flags: Precursor;
GN   Name=pefK; Synonyms=xpsK; OrderedLocusNames=XCC0666;
OS   Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
OS   528 / LMG 568 / P 25).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=190485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Xc1701;
RA   Hu N.-T.T., Hung M.-N., Wang K.C.;
RL   Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25;
RX   PubMed=12024217; DOI=10.1038/417459a;
RA   da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R.,
RA   Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr.,
RA   Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G.,
RA   Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B.,
RA   Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B.,
RA   Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F.,
RA   Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T.,
RA   Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A.,
RA   Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J.,
RA   Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M.,
RA   Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A.,
RA   Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A.,
RA   Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M.,
RA   Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
RT   "Comparison of the genomes of two Xanthomonas pathogens with differing host
RT   specificities.";
RL   Nature 417:459-463(2002).
CC   -!- FUNCTION: Component of the type II secretion system required for the
CC       energy-dependent secretion of extracellular factors such as proteases
CC       and toxins from the periplasm. Plays a role in pseudopilus assembly and
CC       seems to control its length. Interacts with the pseudopilus tip complex
CC       that is critical for the recognition and binding of secretion
CC       substrates. {ECO:0000250|UniProtKB:Q00518}.
CC   -!- SUBUNIT: Type II secretion is composed of four main components: the
CC       outer membrane complex, the inner membrane complex, the cytoplasmic
CC       secretion ATPase and the periplasm-spanning pseudopilus. Interacts with
CC       core component XpsG. {ECO:0000250|UniProtKB:Q00518}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:Q00518}.
CC   -!- PTM: Cleaved by prepilin peptidase. {ECO:0000250|UniProtKB:Q00518}.
CC   -!- SIMILARITY: Belongs to the GSP K family. {ECO:0000305}.
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DR   EMBL; L02630; AAC27381.1; -; Genomic_DNA.
DR   EMBL; AE008922; AAM39982.1; -; Genomic_DNA.
DR   PIR; T12062; T12062.
DR   RefSeq; NP_636058.1; NC_003902.1.
DR   RefSeq; WP_011035906.1; NC_003902.1.
DR   AlphaFoldDB; P34026; -.
DR   SMR; P34026; -.
DR   STRING; 340.xcc-b100_3689; -.
DR   EnsemblBacteria; AAM39982; AAM39982; XCC0666.
DR   GeneID; 58014774; -.
DR   KEGG; xcc:XCC0666; -.
DR   PATRIC; fig|190485.4.peg.731; -.
DR   eggNOG; COG3156; Bacteria.
DR   HOGENOM; CLU_057294_3_0_6; -.
DR   OMA; RKRWIAD; -.
DR   Proteomes; UP000001010; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.10.40.60; -; 1.
DR   InterPro; IPR005628; GspK.
DR   InterPro; IPR038072; GspK_central_sf.
DR   PANTHER; PTHR38831; PTHR38831; 1.
DR   Pfam; PF03934; T2SSK; 1.
DR   PIRSF; PIRSF002786; XcpX; 1.
DR   SUPFAM; SSF158544; SSF158544; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   PROPEP          1..6
FT                   /note="Leader sequence"
FT                   /evidence="ECO:0000250|UniProtKB:Q00518"
FT                   /id="PRO_0000449566"
FT   CHAIN           7..283
FT                   /note="Type II secretion system protein K"
FT                   /id="PRO_0000449567"
FT   TRANSMEM        9..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        31..283
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        281
FT                   /note="A -> V (in Ref. 1; AAC27381)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   283 AA;  30371 MW;  04D840A3B99D5CF9 CRC64;
     MRTMRGAALV LVLWLIALLT AMIGAFALTA RVEALQGSML RNGGQAQEYA RAGMEYALSR
     LSSGEPQARW RPDGRRYRWQ MDDANVEIRI IDESGKVDLN MAEPTLLAGL VRAVGGEAGR
     DVRLAGAIVD WRDGDTLTQP GGGAEDRDYA DAGLPYGAKD GPFETLGELR LVLGMDAELY
     RKLLPHVTLY SGRSRPEARF ATGPVLTAMG LDAQQLLAQR DAPLGLPGSD ATLGGTDTYS
     IESRARLSQG REAVLRAVVR TGASALPGSA YTVLRWEEGA AVQ