ID   GSPN_AERHY              Reviewed;         252 AA.
AC   P41852;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Type II secretion system protein N;
DE            Short=T2SS protein N;
DE   AltName: Full=General secretion pathway protein N;
GN   Name=exeN;
OS   Aeromonas hydrophila.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=644;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ah65;
RX   PubMed=8407845; DOI=10.1128/jb.175.20.6695-6703.1993;
RA   Howard S.P., Critch J., Bedi A.;
RT   "Isolation and analysis of eight exe genes and their involvement in
RT   extracellular protein secretion and outer membrane assembly in Aeromonas
RT   hydrophila.";
RL   J. Bacteriol. 175:6695-6703(1993).
CC   -!- FUNCTION: Involved in a type II secretion system (T2SS, formerly
CC       general secretion pathway, GSP) for the export of proteins.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GSP N family. {ECO:0000305}.
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DR   EMBL; X66504; CAA47135.1; -; Genomic_DNA.
DR   PIR; G49905; G49905.
DR   AlphaFoldDB; P41852; -.
DR   STRING; 1448139.AI20_16480; -.
DR   eggNOG; ENOG5032RTB; Bacteria.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR   GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR   InterPro; IPR000645; T2SS_GspN_CS.
DR   InterPro; IPR022792; T2SS_protein-GspN.
DR   Pfam; PF01203; T2SSN; 1.
DR   PROSITE; PS01142; T2SP_N; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..252
FT                   /note="Type II secretion system protein N"
FT                   /id="PRO_0000195051"
FT   TOPO_DOM        1..4
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        26..252
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   252 AA;  27828 MW;  6C95D9B2C0C12D22 CRC64;
     MKQKVLIAAL FLVAYLGFLL VKLPATLVVR HLPLPPNLVQ LEGVSGTLWS GQVARLQYAS
     ESLTQLRWEL NGWSLLRFAP EVSLRFGDRS GLNGQGVVGW NGAAFGRDIT LNVPAPWVLD
     RVPMRLPFPL TVAGQLQLKV DQFAQGNPWC DNLYGNLHWY GADADTPAGK LPLGDPELKL
     TCIDSRLVAE LKQGSEAVQV LGKLELQPNR QYLFQGTLKP GPELPDQMKQ GLPFLGQPDG
     QGRFPLRYQG RI