ID   GSTCD_DROME             Reviewed;         585 AA.
AC   Q9VJ34; Q95TQ9;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 2.
DT   03-AUG-2022, entry version 133.
DE   RecName: Full=Glutathione S-transferase C-terminal domain-containing protein homolog;
GN   ORFNames=CG10428;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Berkeley; TISSUE=Embryo;
RX   PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA   Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA   Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA   Celniker S.E.;
RT   "A Drosophila full-length cDNA resource.";
RL   Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC   -!- SIMILARITY: Belongs to the GSTCD family. {ECO:0000305}.
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DR   EMBL; AE014134; AAF53723.2; -; Genomic_DNA.
DR   EMBL; AY058604; AAL13833.1; -; mRNA.
DR   RefSeq; NP_609918.1; NM_136074.4.
DR   AlphaFoldDB; Q9VJ34; -.
DR   BioGRID; 61141; 1.
DR   IntAct; Q9VJ34; 6.
DR   STRING; 7227.FBpp0080676; -.
DR   PaxDb; Q9VJ34; -.
DR   DNASU; 35150; -.
DR   EnsemblMetazoa; FBtr0081132; FBpp0080676; FBgn0032724.
DR   GeneID; 35150; -.
DR   KEGG; dme:Dmel_CG10428; -.
DR   UCSC; CG10428-RA; d. melanogaster.
DR   FlyBase; FBgn0032724; CG10428.
DR   VEuPathDB; VectorBase:FBgn0032724; -.
DR   eggNOG; ENOG502QUFE; Eukaryota.
DR   GeneTree; ENSGT00390000004446; -.
DR   HOGENOM; CLU_013673_1_0_1; -.
DR   InParanoid; Q9VJ34; -.
DR   OMA; PRNRIYT; -.
DR   OrthoDB; 911228at2759; -.
DR   PhylomeDB; Q9VJ34; -.
DR   BioGRID-ORCS; 35150; 0 hits in 1 CRISPR screen.
DR   ChiTaRS; CG10428; fly.
DR   GenomeRNAi; 35150; -.
DR   PRO; PR:Q9VJ34; -.
DR   Proteomes; UP000000803; Chromosome 2L.
DR   Bgee; FBgn0032724; Expressed in eye disc (Drosophila) and 30 other tissues.
DR   Genevisible; Q9VJ34; DM.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR025714; Methyltranfer_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF13679; Methyltransf_32; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..585
FT                   /note="Glutathione S-transferase C-terminal domain-
FT                   containing protein homolog"
FT                   /id="PRO_0000316957"
FT   DOMAIN          120..275
FT                   /note="GST C-terminal"
SQ   SEQUENCE   585 AA;  66005 MW;  FE47870009B36D6F CRC64;
     MDQLYLEIEI STQKETTIYT GVSSFLALFT YKFLKDPKNV RVNFVSTKIE GGKIALRSSQ
     LKKELTDRHI TCRDAASLPA IQDLKLPIYE KDGNTFIAGT CAVCRELIAR QPNEELKKLL
     GFKGSCLLAP SEASIWTKFC EVDLVAVVSK LHSGQVLEFV PQEVVRFEQH MNEPVRMHNI
     YKQAREQANQ TENGGKVKRR ERVQIKCTTP KEELLIEHRF AEGISFTIAD IILYPLLRIV
     FQHCGQMLPH FPLTSTWFSE IDSFGDKCAR VLRDLYVPQA IKTPPGELGI PDCEATSLYK
     ADPKRYKPRN RIYTSQLELE AALSKLSSLQ LQFNSDSEHT YGQQLIDWEQ IEPTHAKSSA
     LPKERLERKR QQLENLANAV VSLAQPGDRI VDFCSGTGHL AILLALKLPN CTIIVMENKA
     FSLLQAQKRS NELGLTNCVF YQCNIDYFVG GFKIGASLHA CGTATDIVLQ QCRRAKAHFV
     CCPCCYGSLQ PMPHISYPLS KAFQKVLDTK DYLYIAHSAD QAHEMGTTNC KPETTLQGLH
     CMSVVDTDRL LQAEEAGYQV ILTRLKPEQC TPKNHLLVGR FVKQN