ID   GSTX1_SOLTU             Reviewed;         217 AA.
AC   P32111;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Probable glutathione S-transferase;
DE            EC=2.5.1.18;
DE   AltName: Full=Pathogenesis-related protein 1;
GN   Name=PRP1;
OS   Solanum tuberosum (Potato).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=4113;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2132026;
RA   Taylor J.L., Fritzemeier K.H., Haeuser I., Kombrink E., Rohwer F.,
RA   Schroeder M., Strittmatter G., Hahlbrock K.;
RT   "Structural analysis and activation by fungal infection of a gene encoding
RT   a pathogenesis-related protein in potato.";
RL   Mol. Plant Microbe Interact. 3:72-77(1990).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glutathione + RX = a halide anion + an S-substituted
CC         glutathione + H(+); Xref=Rhea:RHEA:16437, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16042, ChEBI:CHEBI:17792, ChEBI:CHEBI:57925,
CC         ChEBI:CHEBI:90779; EC=2.5.1.18;
CC   -!- INDUCTION: By fungal infection.
CC   -!- SIMILARITY: Belongs to the GST superfamily. HSP26 family.
CC       {ECO:0000305}.
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DR   EMBL; J03679; AAA68430.1; -; Genomic_DNA.
DR   PIR; T07595; T07595.
DR   AlphaFoldDB; P32111; -.
DR   SMR; P32111; -.
DR   STRING; 4113.PGSC0003DMT400005544; -.
DR   PRIDE; P32111; -.
DR   eggNOG; KOG0406; Eukaryota.
DR   InParanoid; P32111; -.
DR   Proteomes; UP000011115; Unassembled WGS sequence.
DR   ExpressionAtlas; P32111; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0004364; F:glutathione transferase activity; IBA:GO_Central.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0006749; P:glutathione metabolic process; IBA:GO_Central.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   CDD; cd03185; GST_C_Tau; 1.
DR   InterPro; IPR010987; Glutathione-S-Trfase_C-like.
DR   InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR   InterPro; IPR004045; Glutathione_S-Trfase_N.
DR   InterPro; IPR004046; GST_C.
DR   InterPro; IPR045074; GST_C_Tau.
DR   InterPro; IPR045073; Omega/Tau-like.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR11260; PTHR11260; 1.
DR   Pfam; PF00043; GST_C; 1.
DR   Pfam; PF02798; GST_N; 1.
DR   SFLD; SFLDG01152; Main.3:_Omega-_and_Tau-like; 1.
DR   SUPFAM; SSF47616; SSF47616; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS50405; GST_CTER; 1.
DR   PROSITE; PS50404; GST_NTER; 1.
PE   2: Evidence at transcript level;
KW   Pathogenesis-related protein; Plant defense; Reference proteome;
KW   Transferase.
FT   CHAIN           1..217
FT                   /note="Probable glutathione S-transferase"
FT                   /id="PRO_0000185872"
FT   DOMAIN          2..81
FT                   /note="GST N-terminal"
FT   DOMAIN          86..210
FT                   /note="GST C-terminal"
FT   BINDING         12
FT                   /ligand="glutathione"
FT                   /ligand_id="ChEBI:CHEBI:57925"
FT                   /evidence="ECO:0000250"
FT   BINDING         39
FT                   /ligand="glutathione"
FT                   /ligand_id="ChEBI:CHEBI:57925"
FT                   /evidence="ECO:0000250"
FT   BINDING         53
FT                   /ligand="glutathione"
FT                   /ligand_id="ChEBI:CHEBI:57925"
FT                   /evidence="ECO:0000250"
FT   BINDING         65..66
FT                   /ligand="glutathione"
FT                   /ligand_id="ChEBI:CHEBI:57925"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   217 AA;  25056 MW;  7B0DBBE216685B4E CRC64;
     MAEVKLLGLR YSPFSHRVEW ALKIKGVKYE FIEEDLQNKS PLLLQSNPIH KKIPVLIHNG
     KCICESMVIL EYIDEAFEGP SILPKDPYDR ALARFWAKYV EDKGAAVWKS FFSKGEEQEK
     AKEEAYEMLK ILDNEFKDKK CFVGDKFGFA DIVANGAALY LGILEEVSGI VLATSEKFPN
     FCAWRDEYCT QNEEYFPSRD ELLIRYRAYI QPVDASK