GT14C_ARATH
ID GT14C_ARATH Reviewed; 384 AA.
AC Q8S8P3;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Beta-glucuronosyltransferase GlcAT14C {ECO:0000305};
DE EC=2.4.1.- {ECO:0000305};
DE AltName: Full=GT14 family glucuronic acid transferase 3 {ECO:0000305};
DE Short=AtGlcAT14C {ECO:0000303|PubMed:24739253};
GN Name=GLCAT14C {ECO:0000303|PubMed:24739253};
GN OrderedLocusNames=At2g37585 {ECO:0000312|Araport:AT2G37585};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=24905498; DOI=10.1111/tpj.12577;
RA Lao J., Oikawa A., Bromley J.R., McInerney P., Suttangkakul A.,
RA Smith-Moritz A.M., Plahar H., Chiu T.-Y., Gonzalez Fernandez-Nino S.M.G.,
RA Ebert B., Yang F., Christiansen K.M., Hansen S.F., Stonebloom S.,
RA Adams P.D., Ronald P.C., Hillson N.J., Hadi M.Z., Vega-Sanchez M.E.,
RA Loque D., Scheller H.V., Heazlewood J.L.;
RT "The plant glycosyltransferase clone collection for functional genomics.";
RL Plant J. 79:517-529(2014).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION.
RX PubMed=24739253; DOI=10.4161/psb.28891;
RA Dilokpimol A., Geshi N.;
RT "Arabidopsis thaliana glucuronosyltransferase in family GT14.";
RL Plant Signal. Behav. 9:E28891-E28891(2014).
CC -!- FUNCTION: Beta-glucuronosyltransferase involved in the biosynthesis of
CC type II arabinogalactan (AG). Modifies both the beta-1,6-linked
CC galactan and beta-1,3-linked galactan present in type II AG.
CC {ECO:0000269|PubMed:24739253}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q9FLD7}; Single-pass type II membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 14 family.
CC {ECO:0000305}.
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DR EMBL; KJ138862; AHL38802.1; -; mRNA.
DR EMBL; AC004684; AAM14996.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09421.1; -; Genomic_DNA.
DR RefSeq; NP_565866.1; NM_129314.3.
DR AlphaFoldDB; Q8S8P3; -.
DR SMR; Q8S8P3; -.
DR STRING; 3702.AT2G37585.1; -.
DR CAZy; GT14; Glycosyltransferase Family 14.
DR iPTMnet; Q8S8P3; -.
DR PaxDb; Q8S8P3; -.
DR PRIDE; Q8S8P3; -.
DR ProteomicsDB; 247137; -.
DR EnsemblPlants; AT2G37585.1; AT2G37585.1; AT2G37585.
DR GeneID; 818335; -.
DR Gramene; AT2G37585.1; AT2G37585.1; AT2G37585.
DR KEGG; ath:AT2G37585; -.
DR Araport; AT2G37585; -.
DR TAIR; locus:505006303; AT2G37585.
DR eggNOG; KOG0799; Eukaryota.
DR HOGENOM; CLU_034994_0_0_1; -.
DR InParanoid; Q8S8P3; -.
DR OMA; KFENVMV; -.
DR OrthoDB; 791893at2759; -.
DR PhylomeDB; Q8S8P3; -.
DR PRO; PR:Q8S8P3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8S8P3; baseline and differential.
DR Genevisible; Q8S8P3; AT.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IDA:TAIR.
DR InterPro; IPR044610; GLCAT14A/B/C.
DR InterPro; IPR003406; Glyco_trans_14.
DR PANTHER; PTHR45719; PTHR45719; 1.
DR Pfam; PF02485; Branch; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Glycosyltransferase; Golgi apparatus; Membrane;
KW Reference proteome; Signal-anchor; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..384
FT /note="Beta-glucuronosyltransferase GlcAT14C"
FT /id="PRO_0000434322"
FT TOPO_DOM 1..11
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 12..34
FT /note="Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 35..384
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT CARBOHYD 156
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 285
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 306
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 384 AA; 44459 MW; 66A057B0B89FAB4E CRC64;
MKRSHISSPR SYSRPAISIF GVFLLFLLVL TLSSRKPSDS SSGLAPNRNL ATKSTIPRFA
YLVTGTKGDG KRVKRLLKAI HHPRNYYLLH LDLEASDEER MELAKYVRSE KKKFENVMVM
GLADLVTEKG PTMLASTLHG VAILLKKAKD WDWFINLSAS DYPLMPQDDI LHIFSYLPRY
LNFIEHTSNI GWKENQRARP IIIDPGFYHL KKSGVFWAKE RRSLPASFKL FMGSTSVALT
RPFLEFCIWG WDNLPRTLLM YYTNFLLSSE GYFQTVVCNN KDYQNTTVNH DLHYTKWDPL
QQRTLNVTVE NFRDMVQSGA PFAREFREDD LVLDKIDIEL LGQTDTGLEL KTPDVVKPTV
SWKRLEKLMV RLLDHENFRA KQCK
