GT47A_PHYPA
ID GT47A_PHYPA Reviewed; 449 AA.
AC A9RGD8;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 64.
DE RecName: Full=Probable glucuronosyltransferase 47 A {ECO:0000303|PubMed:23286876};
DE Short=PpGT47A {ECO:0000303|PubMed:23286876};
DE EC=2.4.-.- {ECO:0000305};
GN Name=GT47A {ECO:0000303|PubMed:23286876};
GN ORFNames=PHYPADRAFT_202121 {ECO:0000312|EMBL:EDQ82227.1};
OS Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; Physcomitrium.
OX NCBI_TaxID=3218;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Gransden 2004;
RX PubMed=18079367; DOI=10.1126/science.1150646;
RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H.,
RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., Tanahashi T.,
RA Sakakibara K., Fujita T., Oishi K., Shin-I T., Kuroki Y., Toyoda A.,
RA Suzuki Y., Hashimoto S.-I., Yamaguchi K., Sugano S., Kohara Y.,
RA Fujiyama A., Anterola A., Aoki S., Ashton N., Barbazuk W.B., Barker E.,
RA Bennetzen J.L., Blankenship R., Cho S.H., Dutcher S.K., Estelle M.,
RA Fawcett J.A., Gundlach H., Hanada K., Heyl A., Hicks K.A., Hughes J.,
RA Lohr M., Mayer K., Melkozernov A., Murata T., Nelson D.R., Pils B.,
RA Prigge M., Reiss B., Renner T., Rombauts S., Rushton P.J., Sanderfoot A.,
RA Schween G., Shiu S.-H., Stueber K., Theodoulou F.L., Tu H., Van de Peer Y.,
RA Verrier P.J., Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M.,
RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S.,
RA Boore J.L.;
RT "The Physcomitrella genome reveals evolutionary insights into the conquest
RT of land by plants.";
RL Science 319:64-69(2008).
RN [2]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RX PubMed=23286876; DOI=10.1186/1471-2229-13-3;
RA Hornblad E., Ulfstedt M., Ronne H., Marchant A.;
RT "Partial functional conservation of IRX10 homologs in physcomitrella patens
RT and Arabidopsis thaliana indicates an evolutionary step contributing to
RT vascular formation in land plants.";
RL BMC Plant Biol. 13:3-3(2013).
CC -!- FUNCTION: Involved in the synthesis of glucuronoxylan hemicellulose in
CC secondary cell walls. {ECO:0000305|PubMed:23286876}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:Q9ZUV3}; Single-pass type II membrane protein
CC {ECO:0000250|UniProtKB:Q9ZUV3}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in newly formed or expanding
CC tissues. {ECO:0000269|PubMed:23286876}.
CC -!- DEVELOPMENTAL STAGE: Mainly observed in the apical region of the adult
CC gametophore, new branches forming on the side of the mature gametophore
CC and in the tissue immediately basal to the immature sporophyte. Also
CC detected in the antheridia. Expressed at the tips of the protonema side
CC branches and in lateral buds of the chloronema.
CC {ECO:0000269|PubMed:23286876}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype and no significant change in
CC monosaccharide composition of the cell walls.
CC {ECO:0000269|PubMed:23286876}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000305}.
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DR EMBL; DS544896; EDQ82227.1; -; Genomic_DNA.
DR RefSeq; XP_001753186.1; XM_001753134.1.
DR AlphaFoldDB; A9RGD8; -.
DR STRING; 3218.PP1S7_455V6.1; -.
DR EnsemblPlants; Pp3c2_6740V3.1; Pp3c2_6740V3.1; Pp3c2_6740.
DR EnsemblPlants; Pp3c2_6740V3.2; Pp3c2_6740V3.2; Pp3c2_6740.
DR Gramene; Pp3c2_6740V3.1; Pp3c2_6740V3.1; Pp3c2_6740.
DR Gramene; Pp3c2_6740V3.2; Pp3c2_6740V3.2; Pp3c2_6740.
DR eggNOG; KOG1021; Eukaryota.
DR HOGENOM; CLU_039682_1_0_1; -.
DR InParanoid; A9RGD8; -.
DR OMA; EHAVQQH; -.
DR OrthoDB; 789556at2759; -.
DR Proteomes; UP000006727; Chromosome 2.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0080116; F:glucuronoxylan glucuronosyltransferase activity; ISS:UniProtKB.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0010417; P:glucuronoxylan biosynthetic process; ISS:UniProtKB.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; ISS:UniProtKB.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR GO; GO:0045492; P:xylan biosynthetic process; ISS:UniProtKB.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR PANTHER; PTHR11062; PTHR11062; 1.
DR Pfam; PF03016; Exostosin; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycoprotein; Glycosyltransferase;
KW Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..449
FT /note="Probable glucuronosyltransferase 47 A"
FT /id="PRO_0000431620"
FT TOPO_DOM 1..31
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 32..52
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 53..449
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT CARBOHYD 172
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT CARBOHYD 433
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ SEQUENCE 449 AA; 51224 MW; E9A5C3DC8B249CFB CRC64;
MEHPLECADS CSLAMSWFCN KKCRGWGLMK RTVVASGLRS VVLLLLFIYF VQDVTAEMGH
QRISGSAGDV LEDNPVGRLK VFIYDIPSKY NTDWLKKDPR CLTHMFAVEE YLHDFLTESP
VRTLNPEEAD WFYTPVYTTC DLTPNGLPLP FKSPRVMRSA ISYISSHWPY WNRTDGADHF
FVVPHDFAAC FHYQEEKAIE RGILPLLKRA TLIQTFGQNH HVCLKEDSIV IPPYAPPERM
QTRLNPPSTP RSIFAYFRGL FYDPGNDPEG GYYARGARAA IWENFKDNPL FDISTEHPAT
YYEDMQRAIF CLCPLGWAPW SPRLVEGVIF GCIPVIIADD IVLPFADAIP WEKIGVFVEE
KDVPILDKIL CTINHEEVLE KQRLLANPAM KQAMLFPRPA KPGDAFHQIL NGLARKLPHD
PSIYLQPGQS FLNWTEGPPG DLYPWGNDL
