GTAC_DICDI
ID GTAC_DICDI Reviewed; 587 AA.
AC Q75JZ1; Q54ZG4;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 91.
DE RecName: Full=GATA zinc finger domain-containing protein 3;
GN Name=gtaC; ORFNames=DDB_G0277589;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
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DR EMBL; AAFI02000020; EAL68612.1; -; Genomic_DNA.
DR RefSeq; XP_642533.1; XM_637441.1.
DR AlphaFoldDB; Q75JZ1; -.
DR SMR; Q75JZ1; -.
DR STRING; 44689.DDB0220470; -.
DR PaxDb; Q75JZ1; -.
DR EnsemblProtists; EAL68612; EAL68612; DDB_G0277589.
DR GeneID; 8621095; -.
DR KEGG; ddi:DDB_G0277589; -.
DR dictyBase; DDB_G0277589; gtaC.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_464978_0_0_1; -.
DR InParanoid; Q75JZ1; -.
DR OMA; IRVEEQW; -.
DR PRO; PR:Q75JZ1; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005737; C:cytoplasm; IDA:dictyBase.
DR GO; GO:0005634; C:nucleus; IDA:dictyBase.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:dictyBase.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IDA:dictyBase.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0140582; P:adenylate cyclase-activating G protein-coupled cAMP receptor signaling pathway; IDA:dictyBase.
DR GO; GO:0031152; P:aggregation involved in sorocarp development; IEP:dictyBase.
DR GO; GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.
DR GO; GO:0031149; P:sorocarp stalk cell differentiation; IMP:dictyBase.
DR GO; GO:0006351; P:transcription, DNA-templated; IDA:dictyBase.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00320; GATA; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 4: Predicted;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..587
FT /note="GATA zinc finger domain-containing protein 3"
FT /id="PRO_0000330436"
FT ZN_FING 500..525
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 53..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..294
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 64479 MW; E20B560348C618B3 CRC64;
MNHQYIPSPI YSDQNSGVHN VNKSLHNLNI NNGNNNYNYS NNNYNNNINN NNNINNNINN
NNNNNNNNNN NNINQYHQNH YDQYSDNNCN NSNSNNINNN NNINNNINNN NINNNNNNIN
SNNNNNNNNN NNNNNNLLKI PQLNISPNGV GGGNGISNGN GVNKIFSKLD LSKVPNSYQL
AHNSSMPNSP TSSNISPSTP TSMALNLSSL KSILDSPPAA PAHSASSSHN NDHRTLNING
NHHNNNNNIN NNINNNVNNN INNGNGNGNG NGNNNNNNNI GVNGSGSSNS SSPSIGFSIP
LLQLKQIGIN NQTSPSQQSQ QQQQQQQQQQ QSQHNGIPLI NTTEIHQRSN PSSATNSPRA
LYYGNESSVE NSPFTTPLSS PRGPISPRAT INSSMSNLQS NIRVEEQWKK IEYYVNDLSH
FIYESIRNKD YSNLSELKEK IDEVVNTSKE IEIIHSIAKS LPPQTRARKK RSTKAEKLQK
DLIGIKRSYV TTPKSKGTYC IFCGTMETPE WRKGPGGHKT LCNACGLHYA KNIKKENQNN
GGSPNPQQNN VTTTTTTTTS TSTNSPNSNG NNFSPESAMS VSKLISD