GTAK_DICDI
ID GTAK_DICDI Reviewed; 650 AA.
AC Q5KSV0; Q1ZXG0;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=GATA zinc finger domain-containing protein 11;
DE AltName: Full=Transcription factor amvA;
GN Name=gtaK; Synonyms=amvA; ORFNames=DDB_G0282811;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION.
RC STRAIN=AX4;
RA Morio T., Uchida K.S., Kuwayama H., Obara S., Katoh M., Yoshino R.,
RA Tashiro K., Kuhara S., Tanaka Y., Urushihara H.;
RT "A transcription factor gene amvA regulates morphogenetic cell movement
RT during development in Dictyostelium discoideum.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Transcription factor that regulates morphogenetic cell
CC movement during development. {ECO:0000269|Ref.1}.
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DR EMBL; AB183264; BAD83848.1; -; mRNA.
DR EMBL; AAFI02000047; EAS66870.1; -; Genomic_DNA.
DR RefSeq; XP_001134553.1; XM_001134553.1.
DR AlphaFoldDB; Q5KSV0; -.
DR STRING; 44689.DDB0232953; -.
DR PaxDb; Q5KSV0; -.
DR EnsemblProtists; EAS66870; EAS66870; DDB_G0282811.
DR GeneID; 8623761; -.
DR KEGG; ddi:DDB_G0282811; -.
DR dictyBase; DDB_G0282811; gtaK.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_421770_0_0_1; -.
DR InParanoid; Q5KSV0; -.
DR OMA; CCACERY; -.
DR PRO; PR:Q5KSV0; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00320; GATA; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Transcription; Transcription regulation;
KW Zinc; Zinc-finger.
FT CHAIN 1..650
FT /note="GATA zinc finger domain-containing protein 11"
FT /id="PRO_0000330444"
FT ZN_FING 522..547
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 16..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 409..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..515
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 650 AA; 72248 MW; 40D2C82E6F00BCDB CRC64;
MENKFLSGSS ELFSSLYNNT NTNSNNNNNN NNNNNNNNNI NNTTTTTTTT TSNNNLKNNF
SNKNNFSFNN SSNSLSSSFG VPSSPPPQKL NNSGYNFNSS SYSSLVPNIK KRSNSLDDNM
SVPTLQNFTN NNNNNNNNNN NNNNNNSNNN SSNNNNNNNN NNNFNNSPTS SPTPYVPTTP
LINSYPSSPF LINQQPLSSS TPFPFNHQPY HIHPFTTLSL NNSNGINNNN HNNNHNNSNN
NNNNNSNSNS NNHNNHNNNN QSIVPQSIHL QSTTPQIQPL SLQPPQQLPT INGPTSTPPS
SSNSTTTTTT TTTTPSTNEN SNNNNNSYNT NNNNKPEIQL IDSGAILECF IELRDLGSSI
SKQSKESMVS GDFANGLERI KVTLSTLTNK IETLDLSIQN IIQNEPRSRI FGNSSDESRV
PVLTRPRRFR KSKVKSKENN HHNNNNNNIN NININNNNCS TPLLQSPQLS SSSPSLNSSH
DGDQHLSSPQ LSSSTPQHKS NGNGNTNSTN NNKRKIGELK QCTSCGTTSS PEWRKGPAGN
QSLCNACGLY FAKLVRREAS LTWKPQSVVS VNDLLCAGKD QKQSNTTSQL TTFINSVEHN
QQIFQQQQQQ QQQQQQQQQQ QQQQQQQQQN HHHQQLQQQQ QQQQQQQLHH