GTDC1_DROME
ID GTDC1_DROME Reviewed; 377 AA.
AC Q9VXN0; Q29QR7;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Glycosyltransferase-like domain-containing protein 1-like;
GN ORFNames=CG15914;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=Berkeley;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9VXN0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9VXN0-2; Sequence=VSP_029383;
CC -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC Glycosyltransferase 4 subfamily. {ECO:0000305}.
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DR EMBL; AE014298; AAF48528.1; -; Genomic_DNA.
DR EMBL; BT024323; ABC86385.1; -; mRNA.
DR RefSeq; NP_573084.1; NM_132856.2. [Q9VXN0-1]
DR AlphaFoldDB; Q9VXN0; -.
DR SMR; Q9VXN0; -.
DR BioGRID; 58890; 1.
DR IntAct; Q9VXN0; 1.
DR STRING; 7227.FBpp0073919; -.
DR CAZy; GT4; Glycosyltransferase Family 4.
DR PaxDb; Q9VXN0; -.
DR DNASU; 32542; -.
DR EnsemblMetazoa; FBtr0074105; FBpp0073919; FBgn0030700. [Q9VXN0-1]
DR GeneID; 32542; -.
DR KEGG; dme:Dmel_CG15914; -.
DR UCSC; CG15914-RA; d. melanogaster. [Q9VXN0-1]
DR FlyBase; FBgn0030700; CG15914.
DR VEuPathDB; VectorBase:FBgn0030700; -.
DR eggNOG; ENOG502QQJ3; Eukaryota.
DR GeneTree; ENSGT00390000006631; -.
DR HOGENOM; CLU_033439_1_0_1; -.
DR InParanoid; Q9VXN0; -.
DR OMA; DNVQPFL; -.
DR PhylomeDB; Q9VXN0; -.
DR BioGRID-ORCS; 32542; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 32542; -.
DR PRO; PR:Q9VXN0; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0030700; Expressed in egg cell and 17 other tissues.
DR ExpressionAtlas; Q9VXN0; baseline and differential.
DR Genevisible; Q9VXN0; DM.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR022701; GlycosylTrfase_1_N.
DR Pfam; PF12038; DUF3524; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..377
FT /note="Glycosyltransferase-like domain-containing protein
FT 1-like"
FT /id="PRO_0000311095"
FT VAR_SEQ 1..127
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12537569"
FT /id="VSP_029383"
SQ SEQUENCE 377 AA; 44158 MW; 1E934487C924A05D CRC64;
MSCAKPHILI IEPFYGGSHK QLIGALIEGL NHGDSEIFSL PAKKWHWRAR TSALHFAQLI
PRDHAFRVLF ASSVLSLAEL IGLRPDLAAC RKIVYFHENQ LIYPVREVKQ RDCQYGFNEI
LSCLAADMVL FNSQFNCNSF LDNVQPFLNM QPDFKIKHIR EQIEKKCQVL YFPVNFERFP
IRKECVKGET AEDLDEKCIH LIWPHRWEHD KNPKLLVDTL CQLHERQVDF KVTICGESYQ
EIPEEFEHIQ EKLGSKLVNF GHLEREEYLK TLLTGDIVIS TADHEFFGVA MLEAAFCGCY
PIAPNKLVYP EIYPKENLYN TSNALTKKLY NFCRMPRVFR KQRDQFFENF NFDRFSAKEL
VPKYLDIFNK HIADEQS
