GTE10_ARATH
ID GTE10_ARATH Reviewed; 1061 AA.
AC Q9FGW9; Q9FGX0;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 2.
DT 25-MAY-2022, entry version 125.
DE RecName: Full=Transcription factor GTE10;
DE AltName: Full=Bromodomain-containing protein GTE10;
DE AltName: Full=Nuclear protein X1;
DE AltName: Full=Protein GLOBAL TRANSCRIPTION FACTOR GROUP E10;
GN Name=GTE10; Synonyms=NPX1; OrderedLocusNames=At5g63320/At5g63330;
GN ORFNames=K9H21.2/K9H21.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12466527; DOI=10.1093/nar/gkf660;
RA Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S.,
RA Richards E.J., Bender J., Mount D.W., Jorgensen R.A.;
RT "Analysis of histone acetyltransferase and histone deacetylase families of
RT Arabidopsis thaliana suggests functional diversification of chromatin
RT modification among multicellular eukaryotes.";
RL Nucleic Acids Res. 30:5036-5055(2002).
RN [6]
RP FUNCTION, INDUCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, AND
RP INTERACTION WITH TIP/NAC091.
RX PubMed=19759343; DOI=10.1104/pp.109.144766;
RA Kim M.J., Shin R., Schachtman D.P.;
RT "A nuclear factor regulates abscisic acid responses in Arabidopsis.";
RL Plant Physiol. 151:1433-1445(2009).
CC -!- FUNCTION: Acts as a negative regulator in plant response to changes in
CC environmental conditions through the control of ABA-regulated gene
CC expression. {ECO:0000269|PubMed:19759343}.
CC -!- SUBUNIT: Interacts with TIP/NAC091. {ECO:0000269|PubMed:19759343}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19759343}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9FGW9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9FGW9-2; Sequence=VSP_040813, VSP_040814;
CC -!- TISSUE SPECIFICITY: Widely expressed in all tissues.
CC {ECO:0000269|PubMed:19759343}.
CC -!- INDUCTION: Up-regulated by potassium deprivation, by salt stress, cold
CC and treatment with exogenous abscisic acid (ABA).
CC {ECO:0000269|PubMed:19759343}.
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10736.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At5g63320 and At5g63330.; Evidence={ECO:0000305};
CC Sequence=BAB10737.1; Type=Erroneous gene model prediction; Note=Was originally thought to correspond to two different genes At5g63320 and At5g63330.; Evidence={ECO:0000305};
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DR EMBL; AB023035; BAB10736.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AB023035; BAB10737.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED97732.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97733.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97734.1; -; Genomic_DNA.
DR EMBL; BT015056; AAT71928.1; -; mRNA.
DR EMBL; BT021130; AAX22265.1; -; mRNA.
DR RefSeq; NP_001154792.1; NM_001161320.2. [Q9FGW9-2]
DR RefSeq; NP_001154793.1; NM_001161321.1. [Q9FGW9-2]
DR RefSeq; NP_201137.5; NM_125727.6. [Q9FGW9-1]
DR AlphaFoldDB; Q9FGW9; -.
DR SMR; Q9FGW9; -.
DR BioGRID; 21695; 1.
DR STRING; 3702.AT5G63320.1; -.
DR iPTMnet; Q9FGW9; -.
DR PaxDb; Q9FGW9; -.
DR PRIDE; Q9FGW9; -.
DR ProteomicsDB; 247196; -. [Q9FGW9-1]
DR EnsemblPlants; AT5G63320.1; AT5G63320.1; AT5G63320. [Q9FGW9-1]
DR EnsemblPlants; AT5G63320.2; AT5G63320.2; AT5G63320. [Q9FGW9-2]
DR EnsemblPlants; AT5G63320.3; AT5G63320.3; AT5G63320. [Q9FGW9-2]
DR GeneID; 836452; -.
DR Gramene; AT5G63320.1; AT5G63320.1; AT5G63320. [Q9FGW9-1]
DR Gramene; AT5G63320.2; AT5G63320.2; AT5G63320. [Q9FGW9-2]
DR Gramene; AT5G63320.3; AT5G63320.3; AT5G63320. [Q9FGW9-2]
DR KEGG; ath:AT5G63320; -.
DR Araport; AT5G63320; -.
DR TAIR; locus:2158564; AT5G63320.
DR eggNOG; KOG1474; Eukaryota.
DR HOGENOM; CLU_007920_0_0_1; -.
DR InParanoid; Q9FGW9; -.
DR OMA; PLRNDKQ; -.
DR PhylomeDB; Q9FGW9; -.
DR PRO; PR:Q9FGW9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGW9; baseline and differential.
DR Genevisible; Q9FGW9; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0009738; P:abscisic acid-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0051365; P:cellular response to potassium ion starvation; IEP:UniProtKB.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR GO; GO:0009409; P:response to cold; IEP:UniProtKB.
DR GO; GO:0009651; P:response to salt stress; IEP:UniProtKB.
DR CDD; cd05506; Bromo_plant1; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; -; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037377; GTE_bromo.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; SSF47370; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51525; NET; 1.
PE 1: Evidence at protein level;
KW Abscisic acid signaling pathway; Alternative splicing; Bromodomain;
KW Coiled coil; Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..1061
FT /note="Transcription factor GTE10"
FT /id="PRO_0000406341"
FT DOMAIN 173..245
FT /note="Bromo"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00035"
FT DOMAIN 304..386
FT /note="NET"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00857"
FT REGION 32..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 106..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 443..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 606..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 588..658
FT /evidence="ECO:0000255"
FT COILED 852..893
FT /evidence="ECO:0000255"
FT COMPBIAS 445..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 769..786
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 799..904
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 973..1006
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 465..477
FT /note="DSDSCSSSGSETD -> GSCLCEPSSISLE (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3, ECO:0000303|Ref.4"
FT /id="VSP_040813"
FT VAR_SEQ 478..1061
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.3, ECO:0000303|Ref.4"
FT /id="VSP_040814"
SQ SEQUENCE 1061 AA; 118973 MW; 11283A1E5FBAF35A CRC64;
MGKARKHSRG RPSGFVPDYM QAVEPDEFVY SERMNSEASP PLKRRRFGLN GDNNGVSKEV
LSLSKMSRSE RKNLVHKLKM ELQQVRDLSK KIASFSSDTV LLSPYNDHSC SDGPRRPPPE
NFATFVGSQG KKRPPVRSDK QRNKKGPSRL NVPTSYTVAS VMKECETLLN RLWSHKSGWP
FRTPVDPVML NIPDYFNVIK HPMDLGTIRS RLCKGEYSSP LDFAADVRLT FSNSIAYNPP
GNQFHTMAQG ISKYFESGWK SIEKKIPMSK PPVIPLTSSA SLESEIPFEV APMRKKEAAM
NDNKLRVEPA KLVMTDGEKK KLGQDLMALE EDFPQKIADL LREQSGSDGQ SGEGEIEIDI
EALSDEILFM VRKLLDDYLR EKKKSMEKSE PCEMEIVHDS GFSNSPLQPS KGDLQIDEDV
DIVGGNDPSV SSHPPLKIEK DAACRNNESS SSSSSSSESG SSSSDSDSCS SSGSETDSIK
ASKPTSREEK KQPGVGIDKK EDDSNSEKIV VNDSLNELDQ LEHTVGEKST TMDAVVLVPD
EETAPPERQI SPDSPDKRYR AAFLKNRFAD TIMKAREKAF TKGEKGDPEK LRIEREEFEK
RLREEKERLQ AEAKAAEEAR RKAKAEAAEK ARREREQERE AARQALQKME KTVEINEGIR
FMEDLQMLRA TGTEGDQLPT SMEVMSPKFS EDMLGLGSFK MESNSNPLEH LGLYMKMDED
EDEEEDPPHF SQRKVEDNPF DRSEKQEHSP HRVEGEDQLV SGNEEPVSQE AHDNGDQEDG
KPINPNEIER QLENMPEQES GVGDKEEQET EVVDMRKQEN EVVDMGVEEV HPLDRSEGRT
LSPHRKERED PRASGNEESV SEKAQDYENQ RDEKINQSER EEQLENVLEQ ESSRDDDTGE
QETEVVGVGK ELSLDKSEGQ TLSPHREEGE NQLDCGNEEL VSQKTQDNGN QEDEKSINKI
EGEEQLANVP EQESRVTEKE EQETGVVDLG EQKSEVVEKG VEENEAVDNG EGVQGTEVSD
KGGNETVVDG NGKVETEVVD KAGQKTDLVD QGEEDIDVEI D
