GTE1_ARATH
ID GTE1_ARATH Reviewed; 386 AA.
AC Q84XV2; O64754; Q56W05;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Transcription factor GTE1;
DE AltName: Full=Bromodomain-containing protein GTE1;
DE AltName: Full=Protein GLOBAL TRANSCRIPTION FACTOR GROUP E1;
DE AltName: Full=Protein IMBIBITION-INDUCIBLE 1;
GN Name=GTE1; Synonyms=IMB1; OrderedLocusNames=At2g34900; ORFNames=F19I3.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, INDUCTION, DEVELOPMENTAL
RP STAGE, DISRUPTION PHENOTYPE, FUNCTION, DOMAIN NET, AND TISSUE SPECIFICITY.
RX PubMed=12969431; DOI=10.1046/j.1365-313x.2003.01848.x;
RA Duque P., Chua N.-H.;
RT "IMB1, a bromodomain protein induced during seed imbibition, regulates
RT ABA- and phyA-mediated responses of germination in Arabidopsis.";
RL Plant J. 35:787-799(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12466527; DOI=10.1093/nar/gkf660;
RA Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S.,
RA Richards E.J., Bender J., Mount D.W., Jorgensen R.A.;
RT "Analysis of histone acetyltransferase and histone deacetylase families of
RT Arabidopsis thaliana suggests functional diversification of chromatin
RT modification among multicellular eukaryotes.";
RL Nucleic Acids Res. 30:5036-5055(2002).
CC -!- FUNCTION: Transcription activator that plays a role in the promotion of
CC seed germination by both negatively and positively regulating the
CC abscisic acid (ABA) and phytochrome A (phyA) transduction pathways,
CC respectively. {ECO:0000269|PubMed:12969431}.
CC -!- INTERACTION:
CC Q84XV2; Q93ZE2: TGA7; NbExp=3; IntAct=EBI-25515825, EBI-541400;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12969431}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q84XV2-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Barely detectable in stems, leaves, siliques, and
CC dry seeds, but was present at considerable levels in roots, flowers and
CC imbibited seeds. {ECO:0000269|PubMed:12969431}.
CC -!- DEVELOPMENTAL STAGE: Down-regulated during germination.
CC {ECO:0000269|PubMed:12969431}.
CC -!- INDUCTION: During seed imbibition. {ECO:0000269|PubMed:12969431}.
CC -!- DOMAIN: The NET domain could serve as an interface to localize
CC different proteins or complexes to chromatin.
CC {ECO:0000269|PubMed:12969431}.
CC -!- DISRUPTION PHENOTYPE: Impaired cotyledon greening during germination.
CC Seeds are deficient in the phytochrome A (phyA)-mediated very-low-
CC fluence response of germination. Mature plants appear normal.
CC {ECO:0000269|PubMed:12969431}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC12830.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY180100; AAO22056.1; -; mRNA.
DR EMBL; AC004238; AAC12830.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09037.1; -; Genomic_DNA.
DR EMBL; AK222242; BAD95432.1; -; mRNA.
DR EMBL; AK230434; BAF02232.1; -; mRNA.
DR EMBL; BT026469; ABH04576.1; -; mRNA.
DR PIR; T00472; T00472.
DR RefSeq; NP_181036.2; NM_129043.5. [Q84XV2-1]
DR AlphaFoldDB; Q84XV2; -.
DR SMR; Q84XV2; -.
DR BioGRID; 3401; 2.
DR IntAct; Q84XV2; 1.
DR STRING; 3702.AT2G34900.1; -.
DR iPTMnet; Q84XV2; -.
DR PaxDb; Q84XV2; -.
DR PRIDE; Q84XV2; -.
DR ProteomicsDB; 247197; -. [Q84XV2-1]
DR EnsemblPlants; AT2G34900.1; AT2G34900.1; AT2G34900. [Q84XV2-1]
DR GeneID; 818055; -.
DR Gramene; AT2G34900.1; AT2G34900.1; AT2G34900. [Q84XV2-1]
DR KEGG; ath:AT2G34900; -.
DR Araport; AT2G34900; -.
DR TAIR; locus:2044722; AT2G34900.
DR eggNOG; KOG1474; Eukaryota.
DR InParanoid; Q84XV2; -.
DR OMA; HAKMARE; -.
DR OrthoDB; 1190089at2759; -.
DR PhylomeDB; Q84XV2; -.
DR PRO; PR:Q84XV2; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q84XV2; baseline and differential.
DR Genevisible; Q84XV2; AT.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0070577; F:lysine-acetylated histone binding; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0010030; P:positive regulation of seed germination; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd05506; Bromo_plant1; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; -; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR017413; GTE1.
DR InterPro; IPR037377; GTE_bromo.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR45926:SF18; PTHR45926:SF18; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PIRSF; PIRSF038154; Transcription_factor_GTE6; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; SSF47370; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51525; NET; 1.
PE 1: Evidence at protein level;
KW Activator; Alternative splicing; Bromodomain; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..386
FT /note="Transcription factor GTE1"
FT /id="PRO_0000406334"
FT DOMAIN 122..194
FT /note="Bromo"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00035"
FT DOMAIN 263..344
FT /note="NET"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00857"
FT REGION 66..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 76
FT /note="N -> S (in Ref. 4; BAD95432)"
FT /evidence="ECO:0000305"
FT CONFLICT 315
FT /note="E -> G (in Ref. 4; BAD95432)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 386 AA; 43442 MW; 7463B51D6AE251EC CRC64;
MSVHVKEEPV LVPNCDVENT ELAVFNGNGE SELENFGTCV DEITDRVNQL EQKVVEVEHF
YSTKDGAAQT NTSKSNSGGK KIAISQPNNS KGNSAGKEKS KGKHVSSPDL MRQFATMFRQ
IAQHKWAWPF LEPVDVKGLG LHDYYKVIEK PMDLGTIKKK MESSEYSNVR EIYADVRLVF
KNAMRYNEEK EDVYVMAESL LEKFEEKWLL IMPKLVEEEK KQVDEEAEKH ANKQLTMEAA
QAEMARDLSN ELYEIDLQLE KLRESVVQRC RKLSTQEKKG LSAALGRLSP EDLSKALKMV
SESNPSFPAG APEVELDIDV QTDVTLWRLK VFVQEALKAA NKSSGGTNAQ NNNNTGTGEI
NKNNAKRRRE ISDAINKASI KRAKKA
