GTE2_ARATH
ID GTE2_ARATH Reviewed; 581 AA.
AC Q9LXA7; F4KI72; Q8GXZ1;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 2.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Transcription factor GTE2;
DE AltName: Full=Bromodomain-containing protein GTE2;
DE AltName: Full=Protein GLOBAL TRANSCRIPTION FACTOR GROUP E2;
GN Name=GTE2; OrderedLocusNames=At5g10550; ORFNames=F12B17_100;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 493-581.
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12466527; DOI=10.1093/nar/gkf660;
RA Pandey R., Mueller A., Napoli C.A., Selinger D.A., Pikaard C.S.,
RA Richards E.J., Bender J., Mount D.W., Jorgensen R.A.;
RT "Analysis of histone acetyltransferase and histone deacetylase families of
RT Arabidopsis thaliana suggests functional diversification of chromatin
RT modification among multicellular eukaryotes.";
RL Nucleic Acids Res. 30:5036-5055(2002).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DOMAIN: The NET domain could serve as an interface to localize
CC different proteins or complexes to chromatin.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC42593.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
CC Sequence=CAB89388.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL353995; CAB89388.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED91562.2; -; Genomic_DNA.
DR EMBL; AK117955; BAC42593.1; ALT_SEQ; mRNA.
DR PIR; T49984; T49984.
DR RefSeq; NP_196617.2; NM_121093.2.
DR AlphaFoldDB; Q9LXA7; -.
DR SMR; Q9LXA7; -.
DR BioGRID; 16198; 2.
DR STRING; 3702.AT5G10550.1; -.
DR iPTMnet; Q9LXA7; -.
DR PaxDb; Q9LXA7; -.
DR PRIDE; Q9LXA7; -.
DR ProteomicsDB; 230167; -.
DR EnsemblPlants; AT5G10550.1; AT5G10550.1; AT5G10550.
DR GeneID; 830920; -.
DR Gramene; AT5G10550.1; AT5G10550.1; AT5G10550.
DR KEGG; ath:AT5G10550; -.
DR Araport; AT5G10550; -.
DR eggNOG; KOG1474; Eukaryota.
DR HOGENOM; CLU_009580_3_0_1; -.
DR InParanoid; Q9LXA7; -.
DR OMA; RKGPEQI; -.
DR OrthoDB; 478559at2759; -.
DR PhylomeDB; Q9LXA7; -.
DR PRO; PR:Q9LXA7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LXA7; baseline and differential.
DR Genevisible; Q9LXA7; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd05506; Bromo_plant1; 1.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; -; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR037377; GTE_bromo.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; SSF47370; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51525; NET; 1.
PE 2: Evidence at transcript level;
KW Bromodomain; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..581
FT /note="Transcription factor GTE2"
FT /id="PRO_0000406335"
FT DOMAIN 186..258
FT /note="Bromo"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00035"
FT DOMAIN 389..470
FT /note="NET"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00857"
FT REGION 130..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..366
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 494..496
FT /note="AEK -> LSE (in Ref. 3; BAC42593)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 581 AA; 64103 MW; 78D22FCCACCE0A65 CRC64;
MAPAVLANLN EPLFLGQCGA VFMRKYTNQP LSGDINNPLF NPNPNPNSIS AYGNNSSKHF
DDSSAYGDYV SFDLDGYTSN QLRELKKRLN SELEEVRFLR ERIESGTFVS GSVYTTQARS
FAGETNDVGV KKTKTKKKKI GHGQKRSNPF ATDEPSLKRH VALDLMSEKV LKSMMTTCGQ
ILVKLMKHKW SWVFLNPVDV VGLGLHDYHR IVDKPMDLGT VKMNLEKGLY RSPIDFASDV
RLTFTNAMSY NPKGQDVYLM AEKLLSQFDV WFNPTLKRFE AQEVKVMGSS SRPGPEDNQR
VWNQNNVAEN ARKGPEQISI AKKLDSVKPL LPTLPPPPVI EITRDPSPPP SPVQPPPPPS
PPPQPVNQVE ASLEVRETNK GRKGKLPKPK AKDPNKREMT MDEKGKLGVN LQELPPEKLG
QLIQILRKRT RDLPQDGDEI ELDIEALDNE TLWELDRFVT NYRKMASKIK RQGFIQNVST
PPRNMPPVTE MGSAEKRGRK GGEAGEEDVD IGEDIPVEDY PSVEIERDGT AAAASGGSSS
SGSFSSSGSS SSSDSESGSS SGSDSDADSV QSPFVEAKEA P
