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GTHB1_CYPCA
ID   GTHB1_CYPCA             Reviewed;         130 AA.
AC   O13050;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Gonadotropin subunit beta-1;
DE   AltName: Full=Follicle-stimulating hormone-like GTH;
DE   AltName: Full=GTH-I-beta;
DE   AltName: Full=Gonadotropin beta-I chain;
DE   Flags: Precursor;
GN   Name=cgba;
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Kobayashi M., Iwasaki M., Kondo H., Yoshiura Y., Watabe S.;
RT   "cDNA cloning of cyprinid gonadotropin I beta subunits.";
RL   Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in gametogenesis and steroidogenesis.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; AB003583; BAA20080.1; -; mRNA.
DR   AlphaFoldDB; O13050; -.
DR   SMR; O13050; -.
DR   Ensembl; ENSCCRT00015002108; ENSCCRP00015001986; ENSCCRG00015001280.
DR   Proteomes; UP000694384; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00069; GHB_like; 1.
DR   Gene3D; 2.10.90.10; -; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR006208; Glyco_hormone_CN.
DR   InterPro; IPR001545; Gonadotropin_bsu.
DR   InterPro; IPR018245; Gonadotropin_bsu_CS.
DR   PANTHER; PTHR11515; PTHR11515; 1.
DR   Pfam; PF00007; Cys_knot; 1.
DR   SMART; SM00068; GHB; 1.
DR   SUPFAM; SSF57501; SSF57501; 1.
DR   PROSITE; PS00261; GLYCO_HORMONE_BETA_1; 1.
DR   PROSITE; PS00689; GLYCO_HORMONE_BETA_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..130
FT                   /note="Gonadotropin subunit beta-1"
FT                   /id="PRO_0000011688"
FT   CARBOHYD        30
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        26..74
FT                   /evidence="ECO:0000250"
FT   DISULFID        40..89
FT                   /evidence="ECO:0000250"
FT   DISULFID        51..105
FT                   /evidence="ECO:0000250"
FT   DISULFID        55..107
FT                   /evidence="ECO:0000250"
FT   DISULFID        110..117
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   130 AA;  14394 MW;  84258CE80651A8C8 CRC64;
     MRMHFVVMVM LLPALMMAGS ECRSSCRLTN ISITVESEEC GSCITIDTTA CAGLCKTQES
     VYRSPLMLSY QNTCNFREWT YETYEFKGCP ARADSVFTYP VALSCECSKC NSDITDCGAL
     SQQTLSCNAH
 
 
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