ID   GTHB1_MORSA             Reviewed;         120 AA.
AC   Q91120;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 2.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Gonadotropin subunit beta-1;
DE   AltName: Full=GTH-I-beta;
DE   AltName: Full=Gonadotropin beta-I chain;
DE   Flags: Precursor;
GN   Name=cgba;
OS   Morone saxatilis (Striped bass) (Perca saxatilis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Moronidae; Morone.
OX   NCBI_TaxID=34816;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Pituitary;
RX   PubMed=8546811; DOI=10.1677/jme.0.0150023;
RA   Hassin S., Elizur A., Zohar Y.;
RT   "Molecular cloning and sequence analysis of striped bass (Morone saxatilis)
RT   gonadotrophin-I and -II subunits.";
RL   J. Mol. Endocrinol. 15:23-35(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   Hassin S.;
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in gametogenesis and steroidogenesis.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; L35070; AAC38035.1; -; mRNA.
DR   PIR; I50993; I50993.
DR   AlphaFoldDB; Q91120; -.
DR   SMR; Q91120; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00069; GHB_like; 1.
DR   Gene3D; 2.10.90.10; -; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR006208; Glyco_hormone_CN.
DR   InterPro; IPR001545; Gonadotropin_bsu.
DR   InterPro; IPR018245; Gonadotropin_bsu_CS.
DR   PANTHER; PTHR11515; PTHR11515; 1.
DR   Pfam; PF00007; Cys_knot; 1.
DR   SMART; SM00068; GHB; 1.
DR   SUPFAM; SSF57501; SSF57501; 1.
DR   PROSITE; PS00689; GLYCO_HORMONE_BETA_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..120
FT                   /note="Gonadotropin subunit beta-1"
FT                   /id="PRO_0000011697"
FT   CARBOHYD        27
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        23..69
FT                   /evidence="ECO:0000250"
FT   DISULFID        35..83
FT                   /evidence="ECO:0000250"
FT   DISULFID        46..95
FT                   /evidence="ECO:0000250"
FT   DISULFID        50..97
FT                   /evidence="ECO:0000250"
FT   DISULFID        100..107
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   120 AA;  13220 MW;  CA6A4EB468B8DF28 CRC64;
     MQLVVMVAVL ALAGAGQGCS FGCHPTNISI QVESCGLTEV IYTTICEGQC YHEDLVYISH
     YERPEQRICN GDWSYEVKHI KGCPVGVTYP VARNCECTTC NTENTDCGRF PEDIPSCLSF