ID   GTHB2_ACALA             Reviewed;         137 AA.
AC   Q90225;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Gonadotropin subunit beta-2;
DE   AltName: Full=GTH-II-beta;
DE   AltName: Full=Gonadotropin beta-II chain;
DE   Flags: Precursor;
GN   Name=cgbb;
OS   Acanthopagrus latus (Yellowfin seabream) (Sparus latus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Spariformes; Sparidae; Acanthopagrus.
OX   NCBI_TaxID=8177;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Tsai H.J., Yang L.T.;
RT   "Molecular cloning and sequencing of yellowfin porgy gonadotropin beta-
RT   subunit cDNA.";
RL   Submitted (JAN-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in gametogenesis and steroidogenesis.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the glycoprotein hormones subunit beta family.
CC       {ECO:0000305}.
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DR   EMBL; L11722; AAA48512.1; -; mRNA.
DR   AlphaFoldDB; Q90225; -.
DR   SMR; Q90225; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   CDD; cd00069; GHB_like; 1.
DR   Gene3D; 2.10.90.10; -; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR006208; Glyco_hormone_CN.
DR   InterPro; IPR001545; Gonadotropin_bsu.
DR   InterPro; IPR018245; Gonadotropin_bsu_CS.
DR   PANTHER; PTHR11515; PTHR11515; 1.
DR   Pfam; PF00007; Cys_knot; 1.
DR   SMART; SM00068; GHB; 1.
DR   SUPFAM; SSF57501; SSF57501; 1.
DR   PROSITE; PS00261; GLYCO_HORMONE_BETA_1; 1.
DR   PROSITE; PS00689; GLYCO_HORMONE_BETA_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hormone; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..137
FT                   /note="Gonadotropin subunit beta-2"
FT                   /id="PRO_0000011678"
FT   CARBOHYD        34
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        30..76
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..91
FT                   /evidence="ECO:0000250"
FT   DISULFID        47..129
FT                   /evidence="ECO:0000250"
FT   DISULFID        55..107
FT                   /evidence="ECO:0000250"
FT   DISULFID        59..109
FT                   /evidence="ECO:0000250"
FT   DISULFID        112..119
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   137 AA;  15330 MW;  7B07407210DB130D CRC64;
     MLPFMLSSFL GASPSIWPLA PAEAFQLPPC QLINQTVSLE KEGCPKCHPV ETTICSGHCI
     TKDPVMKTRY VYQHVCTYRD LHYKTFELPD CPLGVDPTVT YPVAVSCNCG LCAMDTSDCT
     FESLQPNFCM NDIPFYY