ID   GTI1_SCHPO              Reviewed;         720 AA.
AC   O14367;
DT   06-DEC-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Gluconate transport inducer 1;
GN   Name=gti1; ORFNames=SPAC1751.01c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=SP011;
RX   PubMed=9372449; DOI=10.1242/jcs.110.20.2599;
RA   Caspari T.;
RT   "Onset of gluconate-H+ symport in Schizosaccharomyces pombe is regulated by
RT   the kinases Wis1 and Pka1, and requires the gti1+ gene product.";
RL   J. Cell Sci. 110:2599-2608(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Promotes the onset of gluconate uptake upon glucose
CC       starvation. {ECO:0000269|PubMed:9372449}.
CC   -!- SIMILARITY: To S.pombe pac2 in the N-terminal region. {ECO:0000305}.
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DR   EMBL; X92655; CAA63345.1; -; Genomic_DNA.
DR   EMBL; CU329670; CAB61447.1; -; Genomic_DNA.
DR   PIR; T43327; T43327.
DR   RefSeq; NP_592911.1; NM_001018311.2.
DR   AlphaFoldDB; O14367; -.
DR   BioGRID; 278810; 8.
DR   STRING; 4896.SPAC1751.01c.1; -.
DR   iPTMnet; O14367; -.
DR   PaxDb; O14367; -.
DR   PRIDE; O14367; -.
DR   EnsemblFungi; SPAC1751.01c.1; SPAC1751.01c.1:pep; SPAC1751.01c.
DR   GeneID; 2542344; -.
DR   KEGG; spo:SPAC1751.01c; -.
DR   PomBase; SPAC1751.01c; gti1.
DR   VEuPathDB; FungiDB:SPAC1751.01c; -.
DR   eggNOG; KOG4476; Eukaryota.
DR   HOGENOM; CLU_384098_0_0_1; -.
DR   InParanoid; O14367; -.
DR   PRO; PR:O14367; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0035432; P:positive regulation of gluconate transmembrane transport; IMP:PomBase.
DR   GO; GO:0007165; P:signal transduction; ISM:PomBase.
DR   InterPro; IPR018608; Gti1/Pac2.
DR   PANTHER; PTHR28027; PTHR28027; 1.
DR   Pfam; PF09729; Gti1_Pac2; 1.
PE   4: Predicted;
KW   Reference proteome; Transport.
FT   CHAIN           1..720
FT                   /note="Gluconate transport inducer 1"
FT                   /id="PRO_0000083874"
FT   REGION          146..165
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          203..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        215..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   720 AA;  78726 MW;  5CC2CD58ACE7CD87 CRC64;
     MTEPGNLQPT FVGFIGTTVD ALLLFEACRQ NYTHFVDRRP QDRERERLIR SGSVFVFDEV
     QSGIKRWTDG IAWSPSRVIG NFLVYRQLCK KNSVSDRKRS SKSRSDSDEE EVSAFTVSVP
     VDVDVASHVN ISSPSAPSLS DNLFPGSSFS ASSQQNPSSP GSNDIKSEFA AVKNEYVLSP
     TSPTTSAAFP SSFSSLPLVS SKPTGTPFVP KSPPSSSPST TNVSNASTSS APINPRAPQT
     RRESISSTSS IHYCSSSSLS YLHDTERALV GSLTDSYGFK KSGLIKKTIS LMIDGRLHHL
     ISYYTPEDVL NGKLQTPSSF NLFQQLTISK DLLEYKSFRI PPLVEAAESE KISQLSTLEK
     RTLPSFPYNP FFSSSTAEID PYHFQGLTLS TSPISGVESS SLSSAISRNQ SNLSSFQQQQ
     QFSALQSISN NALNENIEQP PIKMAARHSY PNFLQTLPQY MNDVYNPSGL AFNPVNPNAN
     NSFVNLNLIQ FTSPSQALFD YGEGPYVDQK SQYLQPKQPS SNTDSIDQSS YNMSLAASKQ
     FLTSDTQPDV NENYSFISNS IPKNLSTSWN QNMGYHVTNS NSELASQNPL YAQQAVSMES
     MGNAIQSSAY SAMSTPHGGH YDHYAATAKG KNPLAAENHA SGGRLPKVPI PPLSNMRRGS
     VPIIPSSASL PMRTSGNRFC HYSSLNGNHN RISARTNPYP INNQTMLFTE PLSKERGSLS