GTL2_ARATH
ID GTL2_ARATH Reviewed; 619 AA.
AC Q8H181; Q0WU91; Q94F19;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 118.
DE RecName: Full=Trihelix transcription factor GTL2;
DE AltName: Full=GT2-LIKE protein 2;
DE Short=AtGTL2;
DE AltName: Full=Trihelix DNA-binding protein GTL2;
GN OrderedLocusNames=At5g28300; ORFNames=T8M17.70;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable transcription factor that binds specific DNA
CC sequence. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK62408.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF296835; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93787.1; -; Genomic_DNA.
DR EMBL; AF386963; AAK62408.1; ALT_INIT; mRNA.
DR EMBL; AY081484; AAM10046.1; -; mRNA.
DR EMBL; BT000461; AAN17438.1; -; mRNA.
DR EMBL; BT008389; AAP37748.1; -; mRNA.
DR EMBL; AK227285; BAE99307.1; -; mRNA.
DR RefSeq; NP_568506.2; NM_122713.3.
DR AlphaFoldDB; Q8H181; -.
DR SMR; Q8H181; -.
DR BioGRID; 18187; 4.
DR IntAct; Q8H181; 3.
DR STRING; 3702.AT5G28300.1; -.
DR iPTMnet; Q8H181; -.
DR PaxDb; Q8H181; -.
DR PRIDE; Q8H181; -.
DR ProteomicsDB; 247305; -.
DR EnsemblPlants; AT5G28300.1; AT5G28300.1; AT5G28300.
DR GeneID; 832914; -.
DR Gramene; AT5G28300.1; AT5G28300.1; AT5G28300.
DR KEGG; ath:AT5G28300; -.
DR Araport; AT5G28300; -.
DR TAIR; locus:2185319; AT5G28300.
DR eggNOG; KOG4282; Eukaryota.
DR HOGENOM; CLU_469642_0_0_1; -.
DR InParanoid; Q8H181; -.
DR OMA; FEEENRY; -.
DR OrthoDB; 653125at2759; -.
DR PhylomeDB; Q8H181; -.
DR PRO; PR:Q8H181; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8H181; baseline and differential.
DR Genevisible; Q8H181; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0005516; F:calmodulin binding; IDA:TAIR.
DR GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF13837; Myb_DNA-bind_4; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..619
FT /note="Trihelix transcription factor GTL2"
FT /id="PRO_0000405799"
FT DOMAIN 102..154
FT /note="Myb-like 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT DOMAIN 459..526
FT /note="Myb-like 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 11..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 307..361
FT /evidence="ECO:0000255"
FT MOTIF 503..510
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250"
FT COMPBIAS 13..31
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..575
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 280
FT /note="I -> V (in Ref. 4; BAE99307)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 619 AA; 71280 MW; E0471250DE3007FC CRC64;
MFDGGVPEQI HRFIASPPPP PPLPPHQPAA ERSLPFPVSF SSFNTNHQPQ HMLSLDSRKI
IHHHHHHHHH DIKDGGATTG EWIGQTDHDD SDNHHQHHHH HPWCSDEVLA LLRFRSTVEN
WFPEFTWEHT SRKLAEVGFK RSPQECKEKF EEEERRYFNS NNNNNNNTND HQHIGNYNNK
GNNYRIFSEV EEFYHHGHDN EHVSSEVGDN QNKRTNLVEG KGNVGETVQD LMAEDKLRDQ
DQGQVEEASM ENQRNSIEVG KVGNVEDDAK SSSSSSLMMI MKEKKRKKRK KEKERFGVLK
GFCEGLVRNM IAQQEEMHKK LLEDMVKKEE EKIAREEAWK KQEIERVNKE VEIRAQEQAM
ASDRNTNIIK FISKFTDHDL DVVQNPTSPS QDSSSLALRK TQGRRKFQTS SSLLPQTLTP
HNLLTIDKSL EPFSTKTLKP KNQNPKPPKS DDKSDLGKRW PKDEVLALIN IRRSISNMND
DDHKDENSLS TSSKAVPLWE RISKKMLEIG YKRSAKRCKE KWENINKYFR KTKDVNKKRP
LDSRTCPYFH QLTALYSQPP TGTTATTATT ATSARDLDTR PEENRVGSQD PDISVPMHVD
GDGAGDKSNV QFSGFDLEF
