ID   GTPBA_DANRE             Reviewed;         380 AA.
AC   Q6DHF7;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=GTP-binding protein 10;
GN   Name=gtpbp10; ORFNames=zgc:92334;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the ribosome maturation process.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Note=Found in the dense
CC       fibrillar compartment region of the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000255|PROSITE-ProRule:PRU01047}.
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DR   EMBL; BC076017; AAH76017.1; -; mRNA.
DR   RefSeq; NP_001002454.1; NM_001002454.1.
DR   AlphaFoldDB; Q6DHF7; -.
DR   SMR; Q6DHF7; -.
DR   STRING; 7955.ENSDARP00000109111; -.
DR   PaxDb; Q6DHF7; -.
DR   Ensembl; ENSDART00000058970; ENSDARP00000058969; ENSDARG00000040300.
DR   GeneID; 436727; -.
DR   KEGG; dre:436727; -.
DR   CTD; 85865; -.
DR   ZFIN; ZDB-GENE-040718-153; gtpbp10.
DR   eggNOG; KOG1489; Eukaryota.
DR   GeneTree; ENSGT00940000155589; -.
DR   HOGENOM; CLU_011747_2_3_1; -.
DR   InParanoid; Q6DHF7; -.
DR   OMA; VFMVDIF; -.
DR   OrthoDB; 1150635at2759; -.
DR   PhylomeDB; Q6DHF7; -.
DR   TreeFam; TF314774; -.
DR   PRO; PR:Q6DHF7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 16.
DR   Bgee; ENSDARG00000040300; Expressed in liver and 21 other tissues.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   CDD; cd01898; Obg; 1.
DR   Gene3D; 2.70.210.12; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR014100; GTP-bd_Obg/CgtA.
DR   InterPro; IPR006169; GTP1_OBG_dom.
DR   InterPro; IPR036726; GTP1_OBG_dom_sf.
DR   InterPro; IPR045086; OBG_GTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11702; PTHR11702; 2.
DR   Pfam; PF01018; GTP1_OBG; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF002401; GTP_bd_Obg/CgtA; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF82051; SSF82051; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS51883; OBG; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..380
FT                   /note="GTP-binding protein 10"
FT                   /id="PRO_0000312632"
FT   DOMAIN          13..148
FT                   /note="Obg"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01231"
FT   DOMAIN          149..344
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         155..162
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         202..206
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         278..281
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
SQ   SEQUENCE   380 AA;  41757 MW;  827F85ED6D3CCCBD CRC64;
     MVWTSRICFR KYGNFVDNVR LYVRGGTGGM GLPRLGGHGG DGGDVWVVAK KDTRLKQIKD
     KHPDKRFIAG VGSNSSIQAL RGAKGEDVEV FAPTGISVTS DHGRMLGELN REGDKLLVAK
     GGRGGSPQSG FLPNKGQTRN IRLDLKLIAD FGLVGFPNAG KSSLLTALSH AKPKIANYPF
     TTIKPEIGKV MYDDHKQVSV ADLPGLIEGA HVNKGMGHKF LKHVERTKQL MFVVDVCGFQ
     LASKTPFRSA FETVLLLSKE LELYKEELLS KPAILVINKM DLPEAQSHFQ ELEAQLENQG
     ESIHLFSEDV IPKSLMHFTH IVPVSAMTGH GLPLLKSLIR QSLEEQDTID TEAQRSQKIL
     ELRREIPSSS IPSWGLPQPT