ID   GTPBA_XENLA             Reviewed;         383 AA.
AC   Q5U528;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=GTP-binding protein 10;
GN   Name=gtpbp10;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the ribosome maturation process.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Note=Found in the dense
CC       fibrillar compartment region of the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000255|PROSITE-ProRule:PRU01047}.
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DR   EMBL; BC084856; AAH84856.1; -; mRNA.
DR   RefSeq; NP_001088518.1; NM_001095049.1.
DR   AlphaFoldDB; Q5U528; -.
DR   SMR; Q5U528; -.
DR   DNASU; 495388; -.
DR   GeneID; 495388; -.
DR   KEGG; xla:495388; -.
DR   CTD; 495388; -.
DR   Xenbase; XB-GENE-5853256; gtpbp10.S.
DR   OrthoDB; 1150635at2759; -.
DR   Proteomes; UP000186698; Chromosome 6S.
DR   Bgee; 495388; Expressed in testis and 20 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   CDD; cd01898; Obg; 1.
DR   Gene3D; 2.70.210.12; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR014100; GTP-bd_Obg/CgtA.
DR   InterPro; IPR006169; GTP1_OBG_dom.
DR   InterPro; IPR036726; GTP1_OBG_dom_sf.
DR   InterPro; IPR045086; OBG_GTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11702; PTHR11702; 1.
DR   Pfam; PF01018; GTP1_OBG; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF002401; GTP_bd_Obg/CgtA; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF82051; SSF82051; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS51883; OBG; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..383
FT                   /note="GTP-binding protein 10"
FT                   /id="PRO_0000312633"
FT   DOMAIN          13..148
FT                   /note="Obg"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01231"
FT   DOMAIN          149..344
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   REGION          360..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         155..162
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         202..206
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         278..281
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
SQ   SEQUENCE   383 AA;  42067 MW;  20D82FDC6DA4A092 CRC64;
     MVWCCRVLLR KYGNFVDNLR IYVKGGTGGM GLPRLGGQGG NGGDVCLLAK KGVTLKNIKD
     KYPHKRFIGG VGVNSSVRAL KGLAGEVCQV EVPPGIVITN EHGVKIGELD KEGDEIRVAR
     GGHGGIFKTD FLPSKGQTRV IHLDLKLISD VGLVGFPNAG KSSLLGKISH AKPQVADYAF
     TTVKPELGKI MYPDYKQVSV ADLPGLIEGA HYNRGMGHKF LKHIERTKQL LFVVDIAGFQ
     LSAITPCRSA FETVQLLILE LQLYKEELLD KPAVLAVNKM DLPNADEKLG ELLKQLENPT
     GNLHSLPDEL VPERQIEFKH IVPVSAATGQ GLEDLIGCIR KTIDEQADVQ IQELAQERLQ
     SLHKETPRTV KRNFQTSPRH KHH