ID   GTPBA_XENTR             Reviewed;         383 AA.
AC   Q5M8V6;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=GTP-binding protein 10;
GN   Name=gtpbp10;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the ribosome maturation process.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus. Note=Found in the dense
CC       fibrillar compartment region of the nucleolus. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000255|PROSITE-ProRule:PRU01047}.
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DR   EMBL; BC087811; AAH87811.1; -; mRNA.
DR   RefSeq; NP_001011239.1; NM_001011239.1.
DR   AlphaFoldDB; Q5M8V6; -.
DR   SMR; Q5M8V6; -.
DR   STRING; 8364.ENSXETP00000012720; -.
DR   PaxDb; Q5M8V6; -.
DR   DNASU; 496681; -.
DR   GeneID; 496681; -.
DR   KEGG; xtr:496681; -.
DR   CTD; 85865; -.
DR   Xenbase; XB-GENE-5853231; gtpbp10.
DR   eggNOG; KOG1489; Eukaryota.
DR   HOGENOM; CLU_011747_2_3_1; -.
DR   InParanoid; Q5M8V6; -.
DR   OMA; HLEYADI; -.
DR   OrthoDB; 1150635at2759; -.
DR   PhylomeDB; Q5M8V6; -.
DR   TreeFam; TF314774; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IBA:GO_Central.
DR   GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   CDD; cd01898; Obg; 1.
DR   Gene3D; 2.70.210.12; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR014100; GTP-bd_Obg/CgtA.
DR   InterPro; IPR006169; GTP1_OBG_dom.
DR   InterPro; IPR036726; GTP1_OBG_dom_sf.
DR   InterPro; IPR045086; OBG_GTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11702; PTHR11702; 2.
DR   Pfam; PF01018; GTP1_OBG; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF002401; GTP_bd_Obg/CgtA; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF82051; SSF82051; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS51883; OBG; 1.
PE   2: Evidence at transcript level;
KW   GTP-binding; Nucleotide-binding; Nucleus; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..383
FT                   /note="GTP-binding protein 10"
FT                   /id="PRO_0000312634"
FT   DOMAIN          13..148
FT                   /note="Obg"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01231"
FT   DOMAIN          149..344
FT                   /note="OBG-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   REGION          362..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         155..162
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         202..206
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
FT   BINDING         278..281
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01047"
SQ   SEQUENCE   383 AA;  42422 MW;  F7F15C3C223C3603 CRC64;
     MVWCCRPLLR KYGNFIDNLR IYVKGGAGGM GLPRLGGQGG KGGDVKLVAK KEVTLKKIKD
     KFPHKRFIGG VGGNSSVRAL KGQPGEVCQV EVPSGIVITT EHGVKIGELD KEGDEIRVAR
     GGQGGVFQTD FLPSKGQKRI IHLDLKLISD VGLVGFPNAG KSSLLSRISH AKPQVAEYAF
     TTVKPELGRI MYPDYKQISV ADLPGLIEGA HYNRGMGHKF LKHIERTRQL LFVVDVAGFQ
     LSASTLYRSA FETVLLLTLE LQLYKQELLD KPALLAVNKM DLPNANEKFE ELLKQLENPA
     GNFHLLPDEL VPERPIEFKH IIPVSAATGQ GLENLIGCIR KTMDEQADME IRELAQERLQ
     SLQKETSRTV KRNLKNSPQR THH