GTRA_ECOLI
ID GTRA_ECOLI Reviewed; 120 AA.
AC P77682;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Prophage bactoprenol-linked glucose translocase homolog {ECO:0000305};
DE AltName: Full=Bactoprenol-linked glucose translocase homolog from prophage CPS-53;
GN Name=yfdG; OrderedLocusNames=b2350, JW2346;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Involved in O antigen modification. Involved in the
CC translocation of bactoprenol-linked glucose across the cytoplasmic
CC membrane (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the GtrA family. {ECO:0000305}.
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DR EMBL; U00096; AAC75409.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16209.1; -; Genomic_DNA.
DR PIR; C65008; C65008.
DR RefSeq; NP_416851.1; NC_000913.3.
DR RefSeq; WP_000915541.1; NZ_LN832404.1.
DR AlphaFoldDB; P77682; -.
DR SMR; P77682; -.
DR BioGRID; 4260541; 149.
DR STRING; 511145.b2350; -.
DR PaxDb; P77682; -.
DR PRIDE; P77682; -.
DR EnsemblBacteria; AAC75409; AAC75409; b2350.
DR EnsemblBacteria; BAA16209; BAA16209; BAA16209.
DR GeneID; 948821; -.
DR KEGG; ecj:JW2346; -.
DR KEGG; eco:b2350; -.
DR PATRIC; fig|83333.103.peg.3236; -.
DR EchoBASE; EB3883; -.
DR eggNOG; COG2246; Bacteria.
DR HOGENOM; CLU_141008_0_0_6; -.
DR OMA; QATTGRY; -.
DR PhylomeDB; P77682; -.
DR BioCyc; EcoCyc:G7219-MON; -.
DR PRO; PR:P77682; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0008883; F:glutamyl-tRNA reductase activity; IDA:EcoliWiki.
DR GO; GO:0050661; F:NADP binding; IDA:EcoliWiki.
DR GO; GO:0006783; P:heme biosynthetic process; IMP:EcoliWiki.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR InterPro; IPR016480; Glc_translocase_bactprenl-link.
DR InterPro; IPR007267; GtrA.
DR Pfam; PF04138; GtrA; 1.
DR PIRSF; PIRSF006298; GtrA_prd; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..120
FT /note="Prophage bactoprenol-linked glucose translocase
FT homolog"
FT /id="PRO_0000212252"
FT TOPO_DOM 1..9
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 31..33
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..64
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 86..88
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 110..120
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 120 AA; 13226 MW; 881A6B5614875C5A CRC64;
MLKLFAKYTS IGVLNTLIHW VVFGVCIYVA HTNQALANFA GFVVAVSFSF FANAKFTFKA
STTTMRYMLY VGFMGTLSAT VGWAADRCAL PPMITLVTFS AISLVCGFVY SKFIVFRDAK
