ID   GTRA_SHIFL              Reviewed;         124 AA.
AC   P37785;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Bactoprenol-linked glucose translocase;
GN   Name=rfbI; OrderedLocusNames=SF2096, S2218;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PE577 / Serotype 2a;
RX   PubMed=7507920; DOI=10.1128/jb.176.3.733-747.1994;
RA   Morona R., Mavris M., Fallarino A., Manning P.A.;
RT   "Characterization of the rfc region of Shigella flexneri.";
RL   J. Bacteriol. 176:733-747(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Involved in O antigen modification. Involved in the
CC       translocation of bactoprenol-linked glucose across the cytoplasmic
CC       membrane (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the GtrA family. {ECO:0000305}.
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DR   EMBL; X71970; CAA50775.1; -; Genomic_DNA.
DR   EMBL; AE005674; AAN43635.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP17464.1; -; Genomic_DNA.
DR   PIR; D36966; D36966.
DR   RefSeq; NP_707928.1; NC_004337.2.
DR   RefSeq; WP_011069435.1; NZ_WPGV01000030.1.
DR   AlphaFoldDB; P37785; -.
DR   STRING; 198214.SF2096; -.
DR   EnsemblBacteria; AAN43635; AAN43635; SF2096.
DR   EnsemblBacteria; AAP17464; AAP17464; S2218.
DR   GeneID; 1025291; -.
DR   KEGG; sfl:SF2096; -.
DR   KEGG; sfx:S2218; -.
DR   PATRIC; fig|198214.7.peg.2504; -.
DR   HOGENOM; CLU_141008_0_0_6; -.
DR   OrthoDB; 1813832at2; -.
DR   UniPathway; UPA00030; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR016480; Glc_translocase_bactprenl-link.
DR   InterPro; IPR007267; GtrA.
DR   Pfam; PF04138; GtrA; 1.
DR   PIRSF; PIRSF006298; GtrA_prd; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipopolysaccharide biosynthesis; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..124
FT                   /note="Bactoprenol-linked glucose translocase"
FT                   /id="PRO_0000212251"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        75..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  14033 MW;  38193E6FFE42318E CRC64;
     MLKIGKLLTS SFFSYFLIGI VNTALHWGVF YACYNNLAFG QGRSNIVGFI CAATFSFFAN
     ARCSFKVSAT KARYFIFIFF MGAMSYLFGV LFDLLALSPI FTLFTFSLFS LVLGYCASKY
     FIFR