GTRB_ECOLI
ID GTRB_ECOLI Reviewed; 306 AA.
AC P77293;
DT 15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Prophage bactoprenol glucosyl transferase homolog {ECO:0000305};
DE EC=2.4.1.-;
DE AltName: Full=Bactoprenol glucosyl transferase homolog from prophage CPS-53;
GN Name=yfdH; OrderedLocusNames=b2351, JW2347;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Involved in O antigen modification. Catalyzes the transfer of
CC the glucose residue from UDP-glucose to a lipid carrier (By
CC similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC P77293; P77399: fadJ; NbExp=2; IntAct=EBI-545379, EBI-545361;
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. GtrB
CC subfamily. {ECO:0000305}.
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DR EMBL; U00096; AAC75410.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16210.1; -; Genomic_DNA.
DR PIR; D65008; D65008.
DR RefSeq; NP_416852.1; NC_000913.3.
DR RefSeq; WP_000703651.1; NZ_LN832404.1.
DR AlphaFoldDB; P77293; -.
DR SMR; P77293; -.
DR BioGRID; 4260542; 226.
DR DIP; DIP-11997N; -.
DR IntAct; P77293; 1.
DR STRING; 511145.b2351; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR jPOST; P77293; -.
DR PaxDb; P77293; -.
DR PRIDE; P77293; -.
DR EnsemblBacteria; AAC75410; AAC75410; b2351.
DR EnsemblBacteria; BAA16210; BAA16210; BAA16210.
DR GeneID; 949098; -.
DR KEGG; ecj:JW2347; -.
DR KEGG; eco:b2351; -.
DR PATRIC; fig|511145.12.peg.2446; -.
DR EchoBASE; EB3884; -.
DR eggNOG; COG0463; Bacteria.
DR HOGENOM; CLU_033536_0_1_6; -.
DR InParanoid; P77293; -.
DR OMA; PLRMWTY; -.
DR PhylomeDB; P77293; -.
DR BioCyc; EcoCyc:G7220-MON; -.
DR BioCyc; MetaCyc:G7220-MON; -.
DR PRO; PR:P77293; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Glycosyltransferase; Membrane;
KW Reference proteome; Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..306
FT /note="Prophage bactoprenol glucosyl transferase homolog"
FT /id="PRO_0000059194"
FT TOPO_DOM 1..227
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 228..248
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 249..262
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 263..283
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 284..306
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 306 AA; 34635 MW; 600411D3D201B4E6 CRC64;
MKISLVVPVF NEEEAIPIFY KTVREFEELK SYEVEIVFIN DGSKDATESI INALAVSDPL
VVPLSFTRNF GKEPALFAGL DHATGDAIIP IDVDLQDPIE VIPHLIEKWQ AGADMVLAKR
SDRSTDGRLK RKTAEWFYKL HNKISNPKIE ENVGDFRLMS RDVVENIKLM PERNLFMKGI
LSWVGGKTDI VEYVRAERIA GDTKFNGWKL WNLALEGITS FSTFPLRIWT YIGLVVASVA
FIYGAWMILD TIIFGNAVRG YPSLLVSILF LGGIQMIGIG VLGEYIGRTY IETKKRPKYI
IKRVKK
