ID   GTX3C_NEOGO             Reviewed;          30 AA.
AC   P82416;
DT   26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT   26-SEP-2001, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=M-poneritoxin-Ng3c {ECO:0000303|PubMed:26805882};
DE            Short=M-PONTX-Ng3c {ECO:0000303|PubMed:26805882};
DE   AltName: Full=Poneratoxin {ECO:0000305};
DE   AltName: Full=Ponericin-G3 {ECO:0000303|PubMed:11279030};
OS   Neoponera goeldii (Ponerine ant) (Pachycondyla goeldii).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Pachycondyla.
OX   NCBI_TaxID=118888;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=11279030; DOI=10.1074/jbc.m100216200;
RA   Orivel J., Redeker V., Le Caer J.-P., Krier F., Revol-Junelles A.-M.,
RA   Longeon A., Chafotte A., Dejean A., Rossier J.;
RT   "Ponericins, new antibacterial and insecticidal peptides from the venom of
RT   the ant Pachycondyla goeldii.";
RL   J. Biol. Chem. 276:17823-17829(2001).
RN   [2]
RP   REVIEW, AND NOMENCLATURE.
RX   PubMed=26805882; DOI=10.3390/toxins8010030;
RA   Touchard A., Aili S.R., Fox E.G., Escoubas P., Orivel J., Nicholson G.M.,
RA   Dejean A.;
RT   "The biochemical toxin arsenal from ant venoms.";
RL   Toxins 8:1-28(2016).
CC   -!- FUNCTION: Shows a broad spectrum of activity against both Gram-positive
CC       and Gram-negative bacteria. Has also antimicrobial activity against
CC       S.cerevisiae. Has insecticidal and non-hemolytic activity.
CC       {ECO:0000269|PubMed:11279030}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11279030}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:11279030}.
CC   -!- MASS SPECTROMETRY: Mass=3381.36; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:11279030};
CC   -!- SIMILARITY: Belongs to the ponericin-G family. {ECO:0000305}.
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DR   AlphaFoldDB; P82416; -.
DR   SMR; P82416; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR010002; Poneritoxin.
DR   Pfam; PF07442; Ponericin; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide; Secreted;
KW   Toxin.
FT   PEPTIDE         1..30
FT                   /note="M-poneritoxin-Ng3c"
FT                   /evidence="ECO:0000269|PubMed:11279030"
FT                   /id="PRO_0000044187"
SQ   SEQUENCE   30 AA;  3383 MW;  BC0463D0AF140B53 CRC64;
     GWKDWLNKGK EWLKKKGPGI MKAALKAATQ