GTX3G_NEOGO
ID GTX3G_NEOGO Reviewed; 19 AA.
AC P82420;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 26-SEP-2001, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=U1-poneritoxin-Ng3g {ECO:0000303|PubMed:26805882};
DE Short=U1-PONTX-Ng3g {ECO:0000303|PubMed:26805882};
DE AltName: Full=Poneratoxin {ECO:0000305};
DE AltName: Full=Ponericin-G7 {ECO:0000303|PubMed:11279030};
OS Neoponera goeldii (Ponerine ant) (Pachycondyla goeldii).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Ponerinae; Ponerini; Pachycondyla.
OX NCBI_TaxID=118888;
RN [1]
RP PROTEIN SEQUENCE, MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC TISSUE=Venom;
RX PubMed=11279030; DOI=10.1074/jbc.m100216200;
RA Orivel J., Redeker V., Le Caer J.-P., Krier F., Revol-Junelles A.-M.,
RA Longeon A., Chafotte A., Dejean A., Rossier J.;
RT "Ponericins, new antibacterial and insecticidal peptides from the venom of
RT the ant Pachycondyla goeldii.";
RL J. Biol. Chem. 276:17823-17829(2001).
RN [2]
RP REVIEW, AND NOMENCLATURE.
RX PubMed=26805882; DOI=10.3390/toxins8010030;
RA Touchard A., Aili S.R., Fox E.G., Escoubas P., Orivel J., Nicholson G.M.,
RA Dejean A.;
RT "The biochemical toxin arsenal from ant venoms.";
RL Toxins 8:1-28(2016).
CC -!- FUNCTION: Has activity against Gram-positive bacteria and S.cerevisiae.
CC Has non-hemolytic activity. {ECO:0000250|UniProtKB:P82419}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11279030}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000305|PubMed:11279030}.
CC -!- MASS SPECTROMETRY: Mass=1876.14; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:11279030};
CC -!- SIMILARITY: Belongs to the ponericin-G family. {ECO:0000305}.
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DR AlphaFoldDB; P82420; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide; Secreted.
FT PEPTIDE 1..19
FT /note="U1-poneritoxin-Ng3g"
FT /evidence="ECO:0000269|PubMed:11279030"
FT /id="PRO_0000044191"
SQ SEQUENCE 19 AA; 1876 MW; 4DA4876D83F60E8D CRC64;
GLVDVLGKVG GLIKKLLPG