GU01_RAT
ID GU01_RAT Reviewed; 185 AA.
AC P35894;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Putative gustatory receptor clone PTE01;
DE Flags: Fragment;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Fischer; TISSUE=Tongue epithelium;
RX PubMed=8380780; DOI=10.1016/0014-5793(93)81302-g;
RA Abe K., Kusakabe Y., Tanemura K., Emori Y., Arai S.;
RT "Multiple genes for G protein-coupled receptors and their expression in
RT lingual epithelia.";
RL FEBS Lett. 316:253-256(1993).
CC -!- FUNCTION: Possible taste receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Tongue specific.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR PIR; S28996; S28996.
DR AlphaFoldDB; P35894; -.
DR SMR; P35894; -.
DR UCSC; RGD:1590984; rat.
DR PhylomeDB; P35894; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; G-protein coupled receptor; Membrane; Receptor;
KW Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT CHAIN <1..>185
FT /note="Putative gustatory receptor clone PTE01"
FT /id="PRO_0000069665"
FT TRANSMEM <1..11
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 12..42
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..62
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 63..84
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..105
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 106..138
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..160
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 161..182
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..>185
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT NON_TER 1
FT NON_TER 185
SQ SEQUENCE 185 AA; 20605 MW; FCF72E763D578F23 CRC64;
MYLFLSNLSL ADISFTSTTL PKMIVDIQTN NRAISYSGCL TQMSFFMLFG CLDSLLLTAM
AYDRFVAICH PLHYQVIMNP RLCGLLVFLS ILISLLVSQL HNSVVLQLTY FKSVDISHFF
CDPSLLLNLA CSDTFTNNIV MYFVGAISGF LPISGIFFSY YKIVSSILRM PSPGGKYKAF
STCGS