GU03_RAT
ID GU03_RAT Reviewed; 168 AA.
AC P35895;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Putative gustatory receptor clone PTE03;
DE Flags: Fragment;
GN Name=Olr1145;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Fischer; TISSUE=Tongue epithelium;
RX PubMed=8380780; DOI=10.1016/0014-5793(93)81302-g;
RA Abe K., Kusakabe Y., Tanemura K., Emori Y., Arai S.;
RT "Multiple genes for G protein-coupled receptors and their expression in
RT lingual epithelia.";
RL FEBS Lett. 316:253-256(1993).
CC -!- FUNCTION: Possible taste receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- TISSUE SPECIFICITY: Tongue specific.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR PIR; S28997; S28997.
DR AlphaFoldDB; P35895; -.
DR SMR; P35895; -.
DR STRING; 10116.ENSRNOP00000051551; -.
DR PaxDb; P35895; -.
DR UCSC; RGD:1333466; rat.
DR RGD; 1333466; Olr1145.
DR eggNOG; ENOG502T9M5; Eukaryota.
DR InParanoid; P35895; -.
DR PhylomeDB; P35895; -.
DR Proteomes; UP000002494; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Membrane;
KW Receptor; Reference proteome; Transducer; Transmembrane;
KW Transmembrane helix.
FT CHAIN <1..>168
FT /note="Putative gustatory receptor clone PTE03"
FT /id="PRO_0000069666"
FT TOPO_DOM <1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..45
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..67
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 89..121
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 122..143
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 144..165
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 166..>168
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT DISULFID 22..104
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT NON_TER 1
FT NON_TER 168
SQ SEQUENCE 168 AA; 18666 MW; 036335B9C6869D4B CRC64;
TTVPKMLINL QKQNKAISYA GCITQLSFVL LFAGMENFLL AAMAYDRYVA ICKPLRYTAI
MKAHLCLVMT LLSLCISIVD ALLHGLMILR LSFCTFLEIP HYFCELYQVI KLSCSDTLIN
NILVYTMTST LGGVPLGGII FSYFKIISSI LRMPSSGSRH RAFSTCGS