GUCD1_MOUSE
ID GUCD1_MOUSE Reviewed; 239 AA.
AC Q8BZI6; Q147V8; Q3TZX7; Q80XN8; Q8BLZ0;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 2.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Protein GUCD1;
DE AltName: Full=Guanylyl cyclase domain-containing protein 1;
DE AltName: Full=Protein LLN4;
GN Name=Gucd1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J, and NOD; TISSUE=Aorta, Diencephalon, Spleen, and Vein;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Kidney;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC28736.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AK034509; BAC28736.1; ALT_INIT; mRNA.
DR EMBL; AK040832; BAC30713.1; ALT_TERM; mRNA.
DR EMBL; AK157404; BAE34080.1; -; mRNA.
DR EMBL; BC043463; AAH43463.2; -; mRNA.
DR EMBL; BC118613; AAI18614.1; -; mRNA.
DR EMBL; BC119795; AAI19796.1; -; mRNA.
DR CCDS; CCDS35936.1; -.
DR RefSeq; NP_001334130.1; NM_001347201.1.
DR RefSeq; NP_780342.1; NM_175133.2.
DR AlphaFoldDB; Q8BZI6; -.
DR STRING; 10090.ENSMUSP00000043000; -.
DR iPTMnet; Q8BZI6; -.
DR PhosphoSitePlus; Q8BZI6; -.
DR PaxDb; Q8BZI6; -.
DR PRIDE; Q8BZI6; -.
DR Antibodypedia; 9753; 86 antibodies from 14 providers.
DR Ensembl; ENSMUST00000039796; ENSMUSP00000043000; ENSMUSG00000033416.
DR GeneID; 68778; -.
DR KEGG; mmu:68778; -.
DR UCSC; uc007fqk.1; mouse.
DR CTD; 83606; -.
DR MGI; MGI:1916028; Gucd1.
DR VEuPathDB; HostDB:ENSMUSG00000033416; -.
DR eggNOG; KOG4621; Eukaryota.
DR GeneTree; ENSGT00390000000571; -.
DR HOGENOM; CLU_064395_0_1_1; -.
DR InParanoid; Q8BZI6; -.
DR OMA; KRYAGHY; -.
DR OrthoDB; 1348354at2759; -.
DR PhylomeDB; Q8BZI6; -.
DR TreeFam; TF324062; -.
DR BioGRID-ORCS; 68778; 3 hits in 72 CRISPR screens.
DR ChiTaRS; Gucd1; mouse.
DR PRO; PR:Q8BZI6; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q8BZI6; protein.
DR Bgee; ENSMUSG00000033416; Expressed in metanephric proximal tubule and 255 other tissues.
DR ExpressionAtlas; Q8BZI6; baseline and differential.
DR Genevisible; Q8BZI6; MM.
DR InterPro; IPR018616; GUCD1.
DR PANTHER; PTHR31400; PTHR31400; 1.
DR Pfam; PF09778; Guanylate_cyc_2; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..239
FT /note="Protein GUCD1"
FT /id="PRO_0000079575"
FT CONFLICT 157
FT /note="C -> Y (in Ref. 1; BAE34080)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 239 AA; 27264 MW; 576DC4592A9DD641 CRC64;
MRTEAEAAGQ PLEPGDFVQL PVPIIQQLYH WDCGLACSRM VLRYLGQLDD GEFENALQEL
QLTRSIWTID LAYLMRHFGV RHRFCTQTLG VDKGYKNQSF YRKHFDTEET RVNQLFAQAK
ACKVQVEKCT VSVQDIQVHL AQGHVAIVLV NSGVLHCDLC SSPVKYCCFT PSGHRCFCRT
PDYQGHFIVL RGYNRATGCI FYNNPAYADR MCSTSISNFE EARTSYGTDE DILFVYLDS
