ID   GUNA_ACETH              Reviewed;          14 AA.
AC   P0C2S2; P04955;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Endoglucanase A;
DE            Short=EGA;
DE            EC=3.2.1.4;
DE   AltName: Full=Cellulase A;
DE   AltName: Full=Endo-1,4-beta-glucanase;
DE   Flags: Fragment;
GN   Name=celA;
OS   Acetivibrio thermocellus (Hungateiclostridium thermocellum) (Clostridium
OS   thermocellum).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Acetivibrio.
OX   NCBI_TaxID=1515;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=JW20;
RX   PubMed=8664281; DOI=10.1021/bi9524629;
RA   Choi S.K., Ljungdahl L.G.;
RT   "Dissociation of the cellulosome of Clostridium thermocellum in the
RT   presence of ethylenediaminetetraacetic acid occurs with the formation of
RT   trucated polypeptides.";
RL   Biochemistry 35:4897-4905(1996).
CC   -!- FUNCTION: This enzyme catalyzes the endohydrolysis of 1,4-beta-
CC       glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC         cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 8 (cellulase D) family.
CC       {ECO:0000305}.
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DR   IntAct; P0C2S2; 1.
DR   DrugBank; DB02379; Beta-D-Glucose.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Cellulose degradation; Direct protein sequencing;
KW   Glycosidase; Hydrolase; Polysaccharide degradation.
FT   CHAIN           1..>14
FT                   /note="Endoglucanase A"
FT                   /id="PRO_0000007935"
FT   NON_TER         14
SQ   SEQUENCE   14 AA;  1450 MW;  9917F3399EBAA621 CRC64;
     AGVPFNTKTP YGPT