ID   GUNA_RUMFL              Reviewed;         336 AA.
AC   P16169;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 3.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Cellodextrinase A;
DE            EC=3.2.1.-;
GN   Name=celA;
OS   Ruminococcus flavefaciens.
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Ruminococcus.
OX   NCBI_TaxID=1265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FD-1;
RX   PubMed=2129544; DOI=10.1007/bf00633827;
RA   Wang W., Thomson J.A.;
RT   "Nucleotide sequence of the celA gene encoding a cellodextrinase of
RT   Ruminococcus flavefaciens FD-1.";
RL   Mol. Gen. Genet. 222:265-269(1990).
RN   [2]
RP   SEQUENCE REVISION.
RA   Thomson J.A.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Crystalline cellulose degradation.
CC   -!- SUBCELLULAR LOCATION: Secreted. Note=Seems to be exported by a
CC       mechanism other than a leader peptide.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000305}.
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DR   EMBL; X51944; CAA36207.1; -; Genomic_DNA.
DR   AlphaFoldDB; P16169; -.
DR   SMR; P16169; -.
DR   STRING; 641112.ACOK01000037_gene800; -.
DR   CAZy; GH5; Glycoside Hydrolase Family 5.
DR   eggNOG; COG2730; Bacteria.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR018087; Glyco_hydro_5_CS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   PROSITE; PS00659; GLYCOSYL_HYDROL_F5; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Cellulose degradation; Glycosidase; Hydrolase;
KW   Polysaccharide degradation; Secreted.
FT   CHAIN           1..336
FT                   /note="Cellodextrinase A"
FT                   /id="PRO_0000184052"
FT   ACT_SITE        141
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   336 AA;  38687 MW;  7B3E882E5E546711 CRC64;
     MLKSRGIIKG INLGGWMSQC DYSRERLDNF VKENDIKQIA DWGFDHVRLP IDYNIVQNND
     GSVIEDGYNR IDKVVELCRK YGLKLVIDLH KTAGFSFDFG EPESGFFDNK EYQERFYILW
     EEIARRYGHD TDNIVFELLN EVTDEAFIGK WNEISDICIG RIRKIAPEVI ILLGSYHNNA
     ADTVQFLNAP HDDRVVYNFH CYEPLKFTHQ GATWTPDIIP GERMKFEDSE TSEAYFEELF
     STAISTAEKY GTTLYCGEYG VIDVVSAEDS LKWFKVINKV FSKHGISREC GITRKWTSAF
     PTASTTATVR DTEVSVIKTR KAHNCCTLTE VFTRVY