ID   GUTA_BACSU              Reviewed;         463 AA.
AC   O34368;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Probable glucitol transport protein GutA;
GN   Name=gutA; Synonyms=ydjD; OrderedLocusNames=BSU06160;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=9455482; DOI=10.1093/dnares/4.5.335;
RA   Kasahara Y., Nakai S., Ogasawara N., Yata K., Sadaie Y.;
RT   "Sequence analysis of the groESL-cotA region of the Bacillus subtilis
RT   genome, containing the restriction/modification system genes.";
RL   DNA Res. 4:335-339(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Probably involved in glucitol uptake.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000305}.
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DR   EMBL; AB007638; BAA22759.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12435.1; -; Genomic_DNA.
DR   PIR; H69788; H69788.
DR   RefSeq; NP_388497.1; NC_000964.3.
DR   RefSeq; WP_003242688.1; NZ_JNCM01000032.1.
DR   AlphaFoldDB; O34368; -.
DR   SMR; O34368; -.
DR   STRING; 224308.BSU06160; -.
DR   PaxDb; O34368; -.
DR   EnsemblBacteria; CAB12435; CAB12435; BSU_06160.
DR   GeneID; 936004; -.
DR   KEGG; bsu:BSU06160; -.
DR   PATRIC; fig|224308.179.peg.667; -.
DR   eggNOG; COG2211; Bacteria.
DR   InParanoid; O34368; -.
DR   OMA; MYYVKYV; -.
DR   PhylomeDB; O34368; -.
DR   BioCyc; BSUB:BSU06160-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001927; Na/Gal_symport.
DR   InterPro; IPR018043; Na/Gal_symport_CS.
DR   PANTHER; PTHR11328; PTHR11328; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00792; gph; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..463
FT                   /note="Probable glucitol transport protein GutA"
FT                   /id="PRO_0000170764"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        389..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        426..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   463 AA;  51752 MW;  598CF9082AAC8395 CRC64;
     MIGTEKVTAL KAKHQSKSST GLSWFERIGY GFGDMSYNII FQFVNAYLLF YYTDVGGIQP
     AVIATLFLVV RVLDAIFDPI MGLILDKTNT RWGKARPYLL WVAFPFALFT FLCFTTPHFG
     ETGNMVYAYV TYILLGMSFS MQTIPVNSLT GRMTNSVEER TVLTTTRMIL VYIGILLSIS
     CATPLATAIG GEDQAFGFQM TALIYAAVSI VLNLFSFFTV RERIQPKKRK KQGIKKTLSV
     LFKNKPLLML ISSFLAFAIG FNIKLSTMVY YFTYNVNHKE FVFMGTVLFF GAALISNLFI
     PFFSEKWGRK QVMIITAALS LISYAGLHFT PYSSIPLIFI WLFASGFFTT PLNTLAWGMV
     ADCVDYAEWK TGIRADGVVI SSMSFINKLG VALAGSFSAI YLGIAGYVAN TDQTVASLNA
     IKNMNALIPG FFILLSIILI AFYPLTEKRY KHIISELEQR SAR