GUTM_ECOLI
ID GUTM_ECOLI Reviewed; 119 AA.
AC P15081;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1990, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Glucitol operon activator protein;
GN Name=gutM; Synonyms=srlM; OrderedLocusNames=b2706, JW2675;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3062173; DOI=10.1016/0022-2836(88)90193-3;
RA Yamada M., Saier M.H. Jr.;
RT "Positive and negative regulators for glucitol (gut) operon expression in
RT Escherichia coli.";
RL J. Mol. Biol. 203:569-583(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N., Mizobuchi K.,
RA Mori H., Nakade S., Nakamura Y., Nashimoto H., Oshima T., Oyama S.,
RA Saito N., Sampei G., Satoh Y., Sivasundaram S., Tagami H., Takahashi H.,
RA Takeda J., Takemoto K., Uehara K., Wada C., Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-K12
RT genome corresponding to 50.0-68.8 min on the linkage map and analysis of
RT its sequence features.";
RL DNA Res. 4:91-113(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Positive regulator for glucitol operon expression.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; J02708; AAC13414.1; -; Genomic_DNA.
DR EMBL; X13463; CAA31819.1; -; Genomic_DNA.
DR EMBL; U29579; AAA69215.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75748.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA16567.1; -; Genomic_DNA.
DR PIR; S01831; S01831.
DR RefSeq; NP_417186.1; NC_000913.3.
DR RefSeq; WP_000252908.1; NZ_STEB01000027.1.
DR AlphaFoldDB; P15081; -.
DR BioGRID; 4262002; 23.
DR STRING; 511145.b2706; -.
DR PaxDb; P15081; -.
DR PRIDE; P15081; -.
DR EnsemblBacteria; AAC75748; AAC75748; b2706.
DR EnsemblBacteria; BAA16567; BAA16567; BAA16567.
DR GeneID; 66673425; -.
DR GeneID; 948938; -.
DR KEGG; ecj:JW2675; -.
DR KEGG; eco:b2706; -.
DR PATRIC; fig|511145.12.peg.2797; -.
DR EchoBASE; EB0965; -.
DR eggNOG; COG4578; Bacteria.
DR HOGENOM; CLU_124480_1_0_6; -.
DR OMA; QIALGWW; -.
DR PhylomeDB; P15081; -.
DR BioCyc; EcoCyc:PD00345; -.
DR PRO; PR:P15081; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IMP:EcoCyc.
DR InterPro; IPR009693; Glucitol_operon_activator.
DR Pfam; PF06923; GutM; 1.
DR PIRSF; PIRSF011474; Glucitol_operon_activator; 1.
PE 4: Predicted;
KW Activator; DNA-binding; Phosphotransferase system; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..119
FT /note="Glucitol operon activator protein"
FT /id="PRO_0000083878"
FT DNA_BIND 23..29
FT /note="H-T-H motif"
FT /evidence="ECO:0000255"
SQ SEQUENCE 119 AA; 12953 MW; 6AE795316A5A221C CRC64;
MVSALITVAV IAWCAQLALG GWQISRFNRA FDTLCQQGRV GVGRSSGRFK PRVVVAIALD
DQQRIVDTLF MKGLTVFARP QKIPAITGMH AGDLQPDVIF PHDPLSQNAL SLALKLKRG
