ID   GVPC_HALMT              Reviewed;         381 AA.
AC   Q02228; I3R591;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Gas vesicle protein C;
GN   Name=gvpC; OrderedLocusNames=HFX_1695;
OS   Haloferax mediterranei (strain ATCC 33500 / DSM 1411 / JCM 8866 / NBRC
OS   14739 / NCIMB 2177 / R-4) (Halobacterium mediterranei).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=523841;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4;
RX   PubMed=1404376; DOI=10.1016/0022-2836(92)90914-6;
RA   Englert C., Krueger K., Offner S., Pfeifer F.;
RT   "Three different but related gene clusters encoding gas vesicles in
RT   halophilic archaea.";
RL   J. Mol. Biol. 227:586-592(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177 / R-4;
RX   PubMed=22843593; DOI=10.1128/jb.00880-12;
RA   Han J., Zhang F., Hou J., Liu X., Li M., Liu H., Cai L., Zhang B., Chen Y.,
RA   Zhou J., Hu S., Xiang H.;
RT   "Complete genome sequence of the metabolically versatile halophilic
RT   archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-
RT   hydroxyvalerate) producer.";
RL   J. Bacteriol. 194:4463-4464(2012).
CC   -!- FUNCTION: May confer stability to the gas vesicle membranes. Gas
CC       vesicles are small, hollow, gas filled protein structures that are
CC       found in several microbial planktonic microorganisms. They allow the
CC       positioning of the organism at the favorable depth for growth.
CC   -!- SUBCELLULAR LOCATION: Vacuole, gas vesicle membrane; Peripheral
CC       membrane protein; Cytoplasmic side. Note=Binds to the external surface
CC       of the gas vesicle membrane.
CC   -!- SIMILARITY: Belongs to the halobacterial gas vesicle protein type C
CC       family. {ECO:0000305}.
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DR   EMBL; X64701; CAA45944.1; -; Genomic_DNA.
DR   EMBL; CP001868; AFK19401.1; -; Genomic_DNA.
DR   PIR; S28115; S28115.
DR   RefSeq; WP_004056707.1; NZ_CP039139.1.
DR   AlphaFoldDB; Q02228; -.
DR   SMR; Q02228; -.
DR   STRING; 523841.HFX_1695; -.
DR   EnsemblBacteria; AFK19401; AFK19401; HFX_1695.
DR   GeneID; 40157050; -.
DR   KEGG; hme:HFX_1695; -.
DR   eggNOG; arCOG06392; Archaea.
DR   HOGENOM; CLU_060058_0_0_2; -.
DR   OMA; HEAFDAY; -.
DR   OrthoDB; 100599at2157; -.
DR   Proteomes; UP000006469; Chromosome.
DR   GO; GO:0033172; C:gas vesicle shell; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0031412; P:gas vesicle organization; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.1550; -; 1.
DR   InterPro; IPR008639; Gas-vesicle_GvpC_halobac.
DR   InterPro; IPR041920; ROS/MUCR_sf.
DR   InterPro; IPR008807; ROS_MUCR.
DR   Pfam; PF05465; Halo_GVPC; 5.
DR   Pfam; PF05443; ROS_MUCR; 1.
PE   3: Inferred from homology;
KW   Gas vesicle; Membrane; Repeat; Vacuole.
FT   CHAIN           1..381
FT                   /note="Gas vesicle protein C"
FT                   /id="PRO_0000182671"
FT   REPEAT          22..59
FT                   /note="1"
FT   REPEAT          60..84
FT                   /note="2"
FT   REPEAT          85..122
FT                   /note="3"
FT   REPEAT          123..160
FT                   /note="4"
FT   REPEAT          161..192
FT                   /note="5"
FT   REPEAT          193..232
FT                   /note="6"
FT   REPEAT          233..274
FT                   /note="7"
FT   REGION          22..274
FT                   /note="7 X approximate tandem repeats"
FT   REGION          261..333
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..333
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   381 AA;  42654 MW;  9FB48199D0305921 CRC64;
     MSVKDKREKM TATREEFAEV QQAFAAYADE FAADVDDKRD VSELVDGIDT LRTEMNSTND
     AFRAYSEEFA ADVEHFHTSV ADRRDAFDAY ADIFATDVAE MQDVSDLLAA IDDLRAEMDE
     THEAFDAYAD AFVTDVATLR DVSDLLTAIS ELQSEFVSVQ GEFNGYASEF GADIDQFHAV
     VAEKRDGHKD VADAFLQYRE EFHGVEVQSL LDNIAAFQRE MGDYRKAFET TEEAFASFAR
     DFYGQGAAPM ATPLNNAAET AVTGTETEVD IPPIEDSVEP DGEDEDSKAD DVEAEAEVET
     VEMEFGAEMD TEADEDVQSE SVREDDQFLD DETPEDMVQC LVCGEYYQAI TEPHLQTHDM
     TIKKYREEYG EDVPLRPDDK A