ID   GVPD2_HALSA             Reviewed;         492 AA.
AC   Q9HHT2; P33958;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   11-JAN-2001, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Protein GvpD 2;
GN   Name=gvpD2; Synonyms=gvpD; OrderedLocusNames=VNG_6240G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OG   Plasmid pNRC200.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NRC-817;
RX   PubMed=1404376; DOI=10.1016/0022-2836(92)90914-6;
RA   Englert C., Krueger K., Offner S., Pfeifer F.;
RT   "Three different but related gene clusters encoding gas vesicles in
RT   halophilic archaea.";
RL   J. Mol. Biol. 227:586-592(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NRC-817;
RX   PubMed=8763925; DOI=10.1128/jb.178.14.4012-4019.1996;
RA   Krueger K., Pfeifer F.;
RT   "Transcript analysis of the c-vac region and differential synthesis of the
RT   two regulatory gas vesicle proteins GvpD and GvpE in Halobacterium
RT   salinarium PHH4.";
RL   J. Bacteriol. 178:4012-4019(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1; PLASMID=pNRC200;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: May play a role in an energy requiring process such as
CC       assembly of gas vesicles in addition to a possible structural or
CC       regulatory function.
CC   -!- SUBCELLULAR LOCATION: Vacuole, gas vesicle {ECO:0000305}.
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DR   EMBL; X64730; CAA45992.1; -; Genomic_DNA.
DR   EMBL; X94688; CAA64343.1; -; Genomic_DNA.
DR   EMBL; AE004438; AAG20894.1; -; Genomic_DNA.
DR   RefSeq; WP_010904107.1; NZ_BK010831.1.
DR   AlphaFoldDB; Q9HHT2; -.
DR   EnsemblBacteria; AAG20894; AAG20894; VNG_6240G.
DR   GeneID; 5954949; -.
DR   GeneID; 62888162; -.
DR   KEGG; hal:VNG_6240G; -.
DR   PATRIC; fig|64091.14.peg.2242; -.
DR   HOGENOM; CLU_047518_0_0_2; -.
DR   OMA; NICEFAR; -.
DR   OrthoDB; 13916at2157; -.
DR   PhylomeDB; Q9HHT2; -.
DR   Proteomes; UP000000554; Plasmid pNRC200.
DR   GO; GO:0031411; C:gas vesicle; IEA:UniProtKB-SubCell.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR009788; GvpD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07088; GvpD; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   ATP-binding; Gas vesicle; Nucleotide-binding; Plasmid; Reference proteome;
KW   Vacuole.
FT   CHAIN           1..492
FT                   /note="Protein GvpD 2"
FT                   /id="PRO_0000182676"
FT   REGION          355..379
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..371
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         39..46
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        163..164
FT                   /note="AL -> GW (in Ref. 1 and 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        167..168
FT                   /note="DA -> RR (in Ref. 1 and 2)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        469
FT                   /note="L -> V (in Ref. 1 and 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   492 AA;  53929 MW;  655965FD1C36331B CRC64;
     MSARTPLHAP PSHEGIAHFP REIRRFFTGE PGQTLLVNGA PGTGKTLFTI RGLDVLSREG
     DVLYVSTRVD QETVYEMYVE GHAALDRTAL LDLSQDPFGL PMDVDVPFET LNLESLLSWV
     DAISAPATKL TLAFDSWRLV YEYLAARHDS PPSIETVTNQ LVALARDAGV RLVLVSETAT
     QSPLEYIVDG VVTLHVTDNE RGRTRRQLRL EKLRGVRIEN RLQPFTLADG QFKAITPVEL
     STTQSVPDEA TWEPLANPTA RFSTGIRDLD TILSGGFNRG GVVHLDLGAD LSRDAWSVLV
     LPAIRNFLAN EMGVAVVPPK EGSPGLLHND LSAVLSKAVF DTHCHVFETY AGPTRDHDDA
     VDPDRLPGHD TTPTEHGTLS YDPYIARAER IREHSDGPLL HVISMDTAYH AFETRLGDFA
     NYVALHNDAS VLITKPGTAL RTRADRVADM HFRLECAGDA IVLYGETPLT PLLGIGVDQS
     GTIPEITLTE MV