ID   GWA_SEPOF               Reviewed;           2 AA.
AC   P83570;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   07-OCT-2020, entry version 34.
DE   RecName: Full=Neuropeptide GWa;
OS   Sepia officinalis (Common cuttlefish).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Decapodiformes; Sepiida; Sepiina; Sepiidae; Sepia.
OX   NCBI_TaxID=6610 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, MASS SPECTROMETRY, AND AMIDATION AT TRP-2.
RC   TISSUE=Optic lobe;
RX   PubMed=9437704; DOI=10.1016/s0196-9781(97)00241-6;
RA   Henry J., Favrel P., Boucaud-Camou E.;
RT   "Isolation and identification of a novel Ala-Pro-Gly-Trp-amide-related
RT   peptide inhibiting the motility of the mature oviduct in the cuttlefish,
RT   Sepia officinalis.";
RL   Peptides 18:1469-1474(1997).
CC   -!- FUNCTION: Regulatory neuropeptide with myotropic activity targeting the
CC       distal oviduct. Inhibits the motility of the oviduct by decreasing
CC       tonus, frequency and amplitude of contractions.
CC       {ECO:0000269|PubMed:9437704}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- MASS SPECTROMETRY: Mass=259.9; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:9437704};
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..2
FT                   /note="Neuropeptide GWa"
FT                   /id="PRO_0000044143"
FT   MOD_RES         2
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000269|PubMed:9437704"
SQ   SEQUENCE   2 AA;  261 MW;  7378100000000000 CRC64;
     GW