GYF1_CAEEL
ID GYF1_CAEEL Reviewed; 1106 AA.
AC Q09237; A0A2C9C305; A0A2C9C367; A0A2C9C3A1; A0A2C9C3E9; Q09482;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2020, sequence version 4.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=GYF domain-containing protein gyf-1 {ECO:0000305};
GN Name=gyf-1 {ECO:0000312|WormBase:C18H9.3d};
GN ORFNames=C18H9.3 {ECO:0000312|WormBase:C18H9.3d};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=5;
CC Name=d {ECO:0000312|WormBase:C18H9.3d};
CC IsoId=Q09237-1; Sequence=Displayed;
CC Name=a {ECO:0000312|WormBase:C18H9.3a};
CC IsoId=Q09237-2; Sequence=VSP_060467, VSP_060468;
CC Name=b {ECO:0000312|WormBase:C18H9.3b};
CC IsoId=Q09237-3; Sequence=VSP_060468;
CC Name=c {ECO:0000312|WormBase:C18H9.3c};
CC IsoId=Q09237-4; Sequence=VSP_060467;
CC Name=e {ECO:0000312|WormBase:C18H9.3e};
CC IsoId=Q09237-5; Sequence=VSP_060466;
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DR EMBL; BX284602; CCD65263.2; -; Genomic_DNA.
DR EMBL; BX284602; SOF58735.1; -; Genomic_DNA.
DR EMBL; BX284602; SOF58736.1; -; Genomic_DNA.
DR EMBL; BX284602; SOF58737.1; -; Genomic_DNA.
DR EMBL; BX284602; SOF58738.1; -; Genomic_DNA.
DR PIR; B88188; B88188.
DR RefSeq; NP_495360.2; NM_062959.2. [Q09237-2]
DR AlphaFoldDB; Q09237; -.
DR SMR; Q09237; -.
DR BioGRID; 39441; 3.
DR STRING; 6239.C18H9.3; -.
DR EPD; Q09237; -.
DR PaxDb; Q09237; -.
DR PeptideAtlas; Q09237; -.
DR EnsemblMetazoa; C18H9.3a.1; C18H9.3a.1; WBGene00016002. [Q09237-2]
DR EnsemblMetazoa; C18H9.3b.1; C18H9.3b.1; WBGene00016002. [Q09237-3]
DR EnsemblMetazoa; C18H9.3c.1; C18H9.3c.1; WBGene00016002. [Q09237-4]
DR EnsemblMetazoa; C18H9.3d.1; C18H9.3d.1; WBGene00016002. [Q09237-1]
DR EnsemblMetazoa; C18H9.3e.1; C18H9.3e.1; WBGene00016002. [Q09237-5]
DR GeneID; 174103; -.
DR UCSC; C18H9.2; c. elegans. [Q09237-1]
DR UCSC; C18H9.3; c. elegans.
DR CTD; 174103; -.
DR WormBase; C18H9.3a; CE47928; WBGene00016002; gyf-1. [Q09237-2]
DR WormBase; C18H9.3b; CE52358; WBGene00016002; gyf-1. [Q09237-3]
DR WormBase; C18H9.3c; CE52279; WBGene00016002; gyf-1. [Q09237-4]
DR WormBase; C18H9.3d; CE52212; WBGene00016002; gyf-1. [Q09237-1]
DR WormBase; C18H9.3e; CE43752; WBGene00016002; gyf-1. [Q09237-5]
DR eggNOG; KOG1862; Eukaryota.
DR GeneTree; ENSGT00940000168947; -.
DR HOGENOM; CLU_285799_0_0_1; -.
DR InParanoid; Q09237; -.
DR OMA; FHNTGEC; -.
DR OrthoDB; 769617at2759; -.
DR PRO; PR:Q09237; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00016002; Expressed in adult organism and 3 other tissues.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR CDD; cd00072; GYF; 1.
DR Gene3D; 3.30.1490.40; -; 1.
DR InterPro; IPR003169; GYF.
DR InterPro; IPR035445; GYF-like_dom_sf.
DR Pfam; PF02213; GYF; 1.
DR SMART; SM00444; GYF; 1.
DR SUPFAM; SSF55277; SSF55277; 1.
DR PROSITE; PS50829; GYF; 1.
PE 4: Predicted;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..1106
FT /note="GYF domain-containing protein gyf-1"
FT /id="PRO_0000065188"
FT DOMAIN 459..508
FT /note="GYF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00101"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 160..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 383..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 778..811
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..928
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1026..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 584..746
FT /evidence="ECO:0000255"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 257..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1061
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..999
FT /note="Missing (in isoform e)"
FT /evidence="ECO:0000305"
FT /id="VSP_060466"
FT VAR_SEQ 19..22
FT /note="CHFR -> W (in isoform a and isoform c)"
FT /evidence="ECO:0000305"
FT /id="VSP_060467"
FT VAR_SEQ 55..122
FT /note="Missing (in isoform a and isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_060468"
SQ SEQUENCE 1106 AA; 121158 MW; 8FCD203C0B29051A CRC64;
MSSVSSAEPT AQQNFNPSCH FRMRPNAANR GGSISSGNNR SSGFGGGGFD DGGDEISSSA
IAAAAAAVLS SPVVSEFSYT RERLLELAPT GSIMPDALRD QLFFNEKNLP LVSNTPLSEH
EQKLQHNINS SKAMSLLSHA DRASIAAGAA YGSGYGAASG ALQNGQSPTS RWAPKSSWNK
GTPDRGTGTT PRGGGSVGRA SGAFFAGRGG GRIGGENGFG GATNGGSPAA QNEDSPGTYQ
SKFNALRRGG GAGSVGRGGS TTGSAFNTRA DALYNPNDPT DRPKAVNPAA TRSESDEEEE
EGWSKVGSTS RTSTNAAPQS SERPAWARSE SWIQRTQQQQ QQQQQQSTQQ QAQPPITLWN
NREVGSDSTV WKDRNHMVAA VRKASTENHP PQQQQQQQQR SSAPVSAPSR QESESTDVPN
LPIPTYPSDP SAWSNNSMGG GIFYQPTPQP PAPIVKEEPV QFYYMDPTET RRGPFPKDQM
NVWFKAGYFT DESLRVQRGE NGEYKTIGDL KKLHGSSTPF EYLEDIEPPR PILPSIPYPS
ATNPLYPAAF GGVNMWSSMG QPTDVYMMQT NFEQQLVAER NRLLDDHNRR LAEEAEKMAK
FQEAMYRQLT MQHEQRVREQ ELLLQKRAEE IEKREAESKR EEAARLQKLE QEAREIEERK
AALEAEDRRK REIEEYNRMC EKKKNEIIAK EAADRMRLEE ATERERRRLE AESRVAEEKI
RRDRVRAELE AREREEERKR AAERERIARE TASLQQQAEL DAAWAGKKIA TVTTSNSAFT
GAPKQVSPSG SEESDEWIST SKEVKHTKTA PWAAKVEAPQ KSEKTLLEIQ KEEERKFKVE
QEKNAKLKAK EQASNITSAA AIAGDKSGGL WGASKTWAAP ESNSSKSYVS PFLDGPSLEA
ANKMALQKKN SQPKIAVPAK SAPTSAKVAT PVKAKATAVA VSSPATNQKT KKTKEQVATD
ELQQWFVKRF QQFSTQVDSS TLFDCIMSLE NPNEVEDIVM SYLDESKTVK EFVREFIKRR
IAMRAAGGRP DADDLTSART AAAAPSDSNS GSNSNSGNGQ GKKKKKTQKQ VLDGNILGFR
GTAAADRLNK GEIDAVPSAP VNPSRR
