GZF3_YEAST
ID GZF3_YEAST Reviewed; 551 AA.
AC P42944; D6VW74;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 167.
DE RecName: Full=Protein GZF3;
GN Name=GZF3; OrderedLocusNames=YJL110C; ORFNames=J0806;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=7483851; DOI=10.1002/yea.320110909;
RA Rasmussen S.W.;
RT "A 37.5 kb region of yeast chromosome X includes the SME1, MEF2, GSH1 and
RT CSD3 genes, a TCP-1-related gene, an open reading frame similar to the
RT DAL80 gene, and a tRNA(Arg).";
RL Yeast 11:873-883(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=8948101;
RX DOI=10.1002/(sici)1097-0061(199611)12:14<1471::aid-yea30>3.0.co;2-4;
RA Cziepluch C., Kordes E., Pujol A., Jauniaux J.-C.;
RT "Sequencing analysis of a 40.2 kb fragment of yeast chromosome X reveals 19
RT open reading frames including URA2 (5' end), TRK1, PBS2, SPT10, GCD14,
RT RPE1, PHO86, NCA3, ASF1, CCT7, GZF3, two tRNA genes, three remnant delta
RT elements and a Ty4 transposon.";
RL Yeast 12:1471-1474(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- MISCELLANEOUS: Present with 319 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; X85021; CAA59384.1; -; Genomic_DNA.
DR EMBL; Z49385; CAA89405.1; -; Genomic_DNA.
DR EMBL; X86353; CAA60126.1; -; Genomic_DNA.
DR EMBL; BK006943; DAA08690.1; -; Genomic_DNA.
DR PIR; S53377; S53377.
DR RefSeq; NP_012425.1; NM_001181543.1.
DR AlphaFoldDB; P42944; -.
DR SMR; P42944; -.
DR BioGRID; 33646; 194.
DR DIP; DIP-1359N; -.
DR IntAct; P42944; 13.
DR MINT; P42944; -.
DR STRING; 4932.YJL110C; -.
DR iPTMnet; P42944; -.
DR MaxQB; P42944; -.
DR PaxDb; P42944; -.
DR PRIDE; P42944; -.
DR EnsemblFungi; YJL110C_mRNA; YJL110C; YJL110C.
DR GeneID; 853334; -.
DR KEGG; sce:YJL110C; -.
DR SGD; S000003646; GZF3.
DR VEuPathDB; FungiDB:YJL110C; -.
DR eggNOG; KOG1601; Eukaryota.
DR GeneTree; ENSGT00940000176497; -.
DR HOGENOM; CLU_594549_0_0_1; -.
DR InParanoid; P42944; -.
DR OMA; AMLCNAC; -.
DR BioCyc; YEAST:G3O-31564-MON; -.
DR Reactome; R-SCE-9018519; Estrogen-dependent gene expression.
DR PRO; PR:P42944; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P42944; protein.
DR GO; GO:0005634; C:nucleus; IDA:SGD.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IDA:SGD.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0051457; P:maintenance of protein location in nucleus; IPI:SGD.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IMP:SGD.
DR GO; GO:0090295; P:nitrogen catabolite repression of transcription; IMP:SGD.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071; PTHR10071; 1.
DR Pfam; PF00320; GATA; 1.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 1.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..551
FT /note="Protein GZF3"
FT /id="PRO_0000083488"
FT ZN_FING 131..155
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 17..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 467..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..257
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 60520 MW; 807243799BFAB704 CRC64;
MASQATTLRG YNIRKRDNVF EPKSSENLNS LNQSEEEGHI GRWPPLGYEA VSAEQKSAVQ
LRESQAGASI SNNMNFKAND KSFSTSTAGR MSPDTNSLHH ILPKNQVKNN GQTMDANCNN
NVSNDANVPV CKNCLTSTTP LWRRDEHGAM LCNACGLFLK LHGKPRPISL KTDVIKSRNR
KSNTNHAHNL DNFRNQTLIA ELKGDCNIES SGRKANRVTS EDKKKKSSQL LMGTSSTAKI
SKKPKTESKE RSDSHLSATK LEVLMSGDCS RPNLKPKLPK QDTAIYQEKL LTFPSYTDVK
EYSNSAHQSA FIKERSQFNA ASFPLNASHS VTSKTGADSP QLPHLSMLLG SLSSTSISNN
GSEIVSNCNN GIASTAATLA PTSSRTTDSN PSEVPNQIRS TMSSPDIISA KRNDPAPLSF
HMASINDMLE TRDRAISNVK TETTPPHFIP FLQSSKAPCI SKANSQSISN SVSSSDVSGR
KFENHPAKDL GDQLSTKLHK EEEIIKLKTR INELELVTDL YRRHINELDG KCRALEERLQ
RTVKQEGNKG G
