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G_BPPHK
ID   G_BPPHK                 Reviewed;         187 AA.
AC   Q38042; Q8W5S4;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Major spike protein G;
DE   AltName: Full=G protein;
DE   AltName: Full=GPG;
GN   Name=G;
OS   Enterobacteria phage phiK (Bacteriophage phi-K).
OC   Viruses; Monodnaviria; Sangervirae; Phixviricota; Malgrandaviricetes;
OC   Petitvirales; Microviridae; Bullavirinae; Alphatrevirus.
OX   NCBI_TaxID=10848;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (PHI-K AND MUTANT PHI KHT).
RX   PubMed=8827438; DOI=10.1093/oxfordjournals.jbchem.a021348;
RA   Kodaira K., Oki M., Kakikawa M., Kimoto H., Taketo A.;
RT   "The virion proteins encoded by bacteriophage phi K and its host-range
RT   mutant phi KhT: host-range determination and DNA binding properties.";
RL   J. Biochem. 119:1062-1069(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA] OF 165-187.
RX   PubMed=387790; DOI=10.1016/s0021-9258(19)86359-7;
RA   Sims J., Capon D., Dressler D.;
RT   "dnaG (primase)-dependent origins of DNA replication. Nucleotide sequences
RT   of the negative strand initiation sites of bacteriophages St-1, phi K, and
RT   alpha 3.";
RL   J. Biol. Chem. 254:12615-12628(1979).
CC   -!- FUNCTION: Attaches the circulating virion to the bacterial
CC       lipopolysaccharides which serve as receptor for the virus. Determines
CC       the phage host-range. Probably triggers with protein H the injection of
CC       the phage DNA into the host cytoplasm upon conformational changes
CC       induced by the interaction with host lipopolysaccharides (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: The virion is composed of 60 copies each of the F, G, and J
CC       proteins, and 12 copies of the H protein. There are 12 spikes which are
CC       each composed of 5 G and one H proteins.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- MISCELLANEOUS: Phi KhT, a host-range mutant of phi K, can grow on
CC       E.coli C and B, besides K12, and is more thermosensitive than the
CC       parental phage phi K.
CC   -!- SIMILARITY: Belongs to the microvirus G protein family. {ECO:0000305}.
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DR   EMBL; X60323; CAA42892.1; -; Genomic_DNA.
DR   EMBL; M10726; AAA32364.2; -; Genomic_RNA.
DR   PIR; JC4806; JC4806.
DR   RefSeq; NP_043950.1; NC_001730.1.
DR   SMR; Q38042; -.
DR   GeneID; 1261200; -.
DR   KEGG; vg:1261200; -.
DR   Proteomes; UP000002122; Genome.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0019048; P:modulation by virus of host process; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.20; -; 1.
DR   InterPro; IPR016184; Capsid/spike_ssDNA_virus.
DR   InterPro; IPR003515; Spike_G.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF02306; Phage_G; 1.
DR   PIRSF; PIRSF004159; Spike_G; 1.
DR   SUPFAM; SSF88645; SSF88645; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host-virus interaction; Viral attachment to host cell;
KW   Viral genome ejection through host cell envelope;
KW   Viral penetration into host cytoplasm; Virion; Virus entry into host cell.
FT   CHAIN           1..187
FT                   /note="Major spike protein G"
FT                   /id="PRO_0000164894"
FT   VARIANT         75
FT                   /note="A -> S (in phi KhT mutant)"
SQ   SEQUENCE   187 AA;  19569 MW;  C5C5CEC891241701 CRC64;
     MYQIFVTKHD TAIQTSRFSV TGSITPVAPT GNIPVINTGN ITAEHAVVSL YANLTAGTSS
     DGSFIVAMKV DTSPADPNCV ISAGVNLSFA GTSYPIVGIV RFESASDQPT SIAGSQIEHY
     PIEMSVGSGG VCSARDCVTV DIHPRAFGNN VFVGVICSSA KWTSGRVLGT IATTQVIREY
     QVLQPLK
 
 
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