H103_CHICK
ID H103_CHICK Reviewed; 224 AA.
AC P08285;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Histone H1.03;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3597432; DOI=10.1016/s0021-9258(18)47984-7;
RA Coles L.S., Robins A.J., Madley L.K., Wells J.R.E.;
RT "Characterization of the chicken histone H1 gene complement. Generation of
RT a complete set of vertebrate H1 protein sequences.";
RL J. Biol. Chem. 262:9656-9663(1987).
CC -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC chains into higher-order structures.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC ProRule:PRU00837}.
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DR EMBL; M17021; AAA48787.1; -; Genomic_DNA.
DR PIR; D28456; D28456.
DR RefSeq; NP_001292314.1; NM_001305385.1.
DR AlphaFoldDB; P08285; -.
DR SMR; P08285; -.
DR Ensembl; ENSGALT00000079743; ENSGALP00000048542; ENSGALG00000037167.
DR GeneID; 100858354; -.
DR KEGG; gga:100858354; -.
DR CTD; 100858354; -.
DR VEuPathDB; HostDB:geneid_100858354; -.
DR GeneTree; ENSGT00950000183089; -.
DR OMA; PPWVDMI; -.
DR OrthoDB; 1565299at2759; -.
DR PRO; PR:P08285; -.
DR Proteomes; UP000000539; Chromosome 1.
DR Bgee; ENSGALG00000037167; Expressed in skeletal muscle tissue and 9 other tissues.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS51504; H15; 1.
PE 3: Inferred from homology;
KW Chromosome; DNA-binding; Nucleus; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000305"
FT CHAIN 2..224
FT /note="Histone H1.03"
FT /id="PRO_0000195929"
FT DOMAIN 40..113
FT /note="H15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..166
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..224
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 224 AA; 22526 MW; 94B782DA0158CE22 CRC64;
MAETAPVAAP DVAAAPTPAK AAPAKKPKKA AGGAKARKPA GPSVTELITK AVSASKERKG
LSLAALKKAL AAGGYDVEKS NSRIKLGLKS LVSKGTLVQT KGTGASGSFR LSKKSGDVKE
KAPKKKTPAA KPKKPAAKKP AAAAKKPKKA VAVKKSPKKA KKPAAAATKK AAKSPKKVTK
AAKPKKAVAV KSPAKAKAVK PKAAKPKATK PKAAKAKKAA PKKK
