ID   H10_XENTR               Reviewed;         196 AA.
AC   Q6NVM0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Histone H1.0;
DE   AltName: Full=Histone H1(0);
DE   AltName: Full=Histone H5;
GN   Name=h1-0;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures. The histones H1.0 are found in
CC       cells that are in terminal stages of differentiation or that have low
CC       rates of cell division (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837}.
CC       Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837}.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; BC067985; AAH67985.1; -; mRNA.
DR   RefSeq; NP_998836.1; NM_213671.1.
DR   AlphaFoldDB; Q6NVM0; -.
DR   SMR; Q6NVM0; -.
DR   PaxDb; Q6NVM0; -.
DR   DNASU; 407939; -.
DR   Ensembl; ENSXETT00000101169; ENSXETP00000093071; ENSXETG00000041200.
DR   GeneID; 407939; -.
DR   KEGG; xtr:407939; -.
DR   CTD; 3005; -.
DR   Xenbase; XB-GENE-480028; h1-0.
DR   eggNOG; KOG4012; Eukaryota.
DR   HOGENOM; CLU_052897_1_1_1; -.
DR   InParanoid; Q6NVM0; -.
DR   OMA; PTYSDMI; -.
DR   OrthoDB; 1565299at2759; -.
DR   PhylomeDB; Q6NVM0; -.
DR   TreeFam; TF313664; -.
DR   Reactome; R-XTR-140342; Apoptosis induced DNA fragmentation.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000041200; Expressed in heart and 21 other tissues.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   2: Evidence at transcript level;
KW   Chromosome; DNA condensation; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..196
FT                   /note="Histone H1.0"
FT                   /id="PRO_0000259965"
FT   DOMAIN          24..97
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..196
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   196 AA;  21006 MW;  CD7AA64A44AE8026 CRC64;
     MTENSAAAPA GKPKRSKASK KATDHPKYSD MILAAVQAEK SRSGSSRQSI QKYIKNHYKV
     GENADSQIKL SIKRLVTSGT LKQTKGVGAS GSFRLAKADE GKKPAKKPKK EIKKAASPKK
     AAKPKKAAKS PAKAKKPKVA EKKVKKPAKK KPAPSPKKAK KTKTVKAKPV RASRVKKAKP
     SKPKAKASPK KSGRKK