H11R_CHICK
ID H11R_CHICK Reviewed; 219 AA.
AC P08288;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Histone H1.11R;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3597432; DOI=10.1016/s0021-9258(18)47984-7;
RA Coles L.S., Robins A.J., Madley L.K., Wells J.R.E.;
RT "Characterization of the chicken histone H1 gene complement. Generation of
RT a complete set of vertebrate H1 protein sequences.";
RL J. Biol. Chem. 262:9656-9663(1987).
CC -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC chains into higher-order structures.
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC ProRule:PRU00837}.
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DR EMBL; M17020; AAA48790.1; -; Genomic_DNA.
DR PIR; C28456; C28456.
DR RefSeq; NP_001075172.1; NM_001081703.1.
DR AlphaFoldDB; P08288; -.
DR SMR; P08288; -.
DR STRING; 9031.ENSGALP00000019205; -.
DR PaxDb; P08288; -.
DR GeneID; 427896; -.
DR KEGG; gga:427896; -.
DR CTD; 427896; -.
DR VEuPathDB; HostDB:geneid_427896; -.
DR eggNOG; KOG4012; Eukaryota.
DR OrthoDB; 1565299at2759; -.
DR PRO; PR:P08288; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR CDD; cd00073; H15; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005819; H1/H5.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR PRINTS; PR00624; HISTONEH5.
DR SMART; SM00526; H15; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS51504; H15; 1.
PE 3: Inferred from homology;
KW Chromosome; DNA-binding; Nucleus; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000305"
FT CHAIN 2..219
FT /note="Histone H1.11R"
FT /id="PRO_0000195932"
FT DOMAIN 38..111
FT /note="H15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..164
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..219
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 21803 MW; 3EA764B26806705B CRC64;
MAETAPAAAP AAAPAPAAKA AAKKPKKAAG GAKARKPAGP SVTELITKAV SASKERKGLS
LAALKKALAA GGYDVEKNNS RIKLGLKSLV SKGTLVQTKG TGASGSFRLS KKPGEGLEKA
PKKKASAAKP KKAAAKKPAA AAKKPKKAVA VKKSPKKAKK PAASATKKSV KSPKKAAKPK
KAVAAKSPAK AKAVKPKAAK PKAAKPKAAK AKKAAAKKK
