ID   H12_GLYBA               Reviewed;         232 AA.
AC   P40264;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Histone H1-II;
OS   Glyptotendipes barbipes (Midge) (Chironomus barbipes).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Chironominae; Glyptotendipes.
OX   NCBI_TaxID=33399;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7806560; DOI=10.1083/jcb.127.6.1789;
RA   Schulze E., Nagel S., Gavenis K., Grossbach U.;
RT   "Structurally divergent histone H1 variants in chromosomes containing
RT   highly condensed interphase chromatin.";
RL   J. Cell Biol. 127:1789-1798(1994).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; L29102; AAA62321.1; -; Genomic_DNA.
DR   AlphaFoldDB; P40264; -.
DR   SMR; P40264; -.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus.
FT   CHAIN           1..232
FT                   /note="Histone H1-II"
FT                   /id="PRO_0000195974"
FT   DOMAIN          39..114
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          103..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..138
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..170
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..208
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..232
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   232 AA;  24316 MW;  5C481A9F37452D4E CRC64;
     MSDPAPEVAP AAPVASPAKA KKEKKPKSDK PKKPKAPRTH PPVSEMVVNA IKTLKERGGS
     SLQAIKKFLV AQYKVDVEKL APFIKKYLKG GAVVKGELLQ TKGKGASGSF KLPAAAKKEK
     VAKKPMKATG EKKPKAAAKP KKAGEKKKSI AKKPKAATAT KVKKPVAKST KKQAAVKPAA
     KKAAPKPKAV PKPKAAKPKK EAKPKKAAAP KAAKKPAQKK PKATKKPAAK KA