H13E_PARAN
ID H13E_PARAN Reviewed; 27 AA.
AC Q99283;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=Histone H1.3, embryonic;
DE Flags: Fragment;
OS Parechinus angulosus (Angulate sea urchin) (Cidaris angulosus).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Echinidae; Parechinus.
OX NCBI_TaxID=7658;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE.
RC TISSUE=Embryo {ECO:0000269|PubMed:6615845};
RX PubMed=6615845; DOI=10.1016/0167-4838(83)90106-1;
RA de Groot P., Strickland W.N., Brandt W.F., von Holt C.;
RT "The identification by sequence homology of stage-specific sea urchin
RT embryo histones H1.";
RL Biochim. Biophys. Acta 747:276-283(1983).
CC -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC chains into higher-order structures.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome.
CC -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC ProRule:PRU00837}.
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DR AlphaFoldDB; Q99283; -.
DR SMR; Q99283; -.
DR GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005818; Histone_H1/H5_H15.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00538; Linker_histone; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS51504; H15; 1.
PE 1: Evidence at protein level;
KW Chromosome; Direct protein sequencing; DNA-binding; Nucleus.
FT CHAIN <1..>27
FT /note="Histone H1.3, embryonic"
FT /id="PRO_0000273526"
FT DOMAIN 1..27
FT /note="H15"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT NON_TER 1
FT /evidence="ECO:0000303|PubMed:6615845"
FT NON_TER 27
FT /evidence="ECO:0000303|PubMed:6615845"
SQ SEQUENCE 27 AA; 2849 MW; F39B694251D4946B CRC64;
HVVAAITALK ERGGSSHQAL KKYKAAN