ID   H1B_STRPU               Reviewed;         211 AA.
AC   P15869;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Histone H1-beta, late embryonic;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC   Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2837660; DOI=10.1128/mcb.8.4.1842-1844.1988;
RA   Lai Z.-C., Childs G.;
RT   "Characterization of the structure and transcriptional patterns of the gene
RT   encoding the late histone subtype H1-beta of the sea urchin
RT   Strongylocentrotus purpuratus.";
RL   Mol. Cell. Biol. 8:1842-1844(1988).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; M20314; AAA30052.1; -; Genomic_DNA.
DR   PIR; A28100; A28100.
DR   RefSeq; NP_999723.1; NM_214558.1.
DR   AlphaFoldDB; P15869; -.
DR   SMR; P15869; -.
DR   STRING; 7668.SPU_016087-tr; -.
DR   EnsemblMetazoa; NM_214558; NP_999723; LOC373354.
DR   GeneID; 373354; -.
DR   KEGG; spu:373354; -.
DR   eggNOG; KOG4012; Eukaryota.
DR   HOGENOM; CLU_052897_1_2_1; -.
DR   OMA; GASHPPY; -.
DR   OrthoDB; 1565299at2759; -.
DR   PhylomeDB; P15869; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0031492; F:nucleosomal DNA binding; IBA:GO_Central.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IBA:GO_Central.
DR   GO; GO:0045910; P:negative regulation of DNA recombination; IBA:GO_Central.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..211
FT                   /note="Histone H1-beta, late embryonic"
FT                   /id="PRO_0000195944"
FT   DOMAIN          17..91
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..119
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        120..172
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..211
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   211 AA;  22169 MW;  9F214581334BBE7A CRC64;
     MAAEQKKVAK KPRAKPAHPS SSEMVLAAIT ALKERGGSSA QAIRKYIEKN YTVDIKKQAI
     FIKRALITGV EKGTLVQVKG KGASGSFKLG KKKEGKSDAQ KAPDAAKKAK LAAKKKEAKE
     KKAARSKAKK EKLAAKKASK KTTKKVKKPA AKKAKKPAAK KAAKKPAAKK PAAKKAAAKP
     APAKKAAKKP AAKKAAKKVA KKPAAKKAAK K