ID   H1B_XENLA               Reviewed;         220 AA.
AC   P06893;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Histone H1B;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] (GENE CLUSTER X1H1).
RX   PubMed=3863963; DOI=10.1016/0022-2836(85)90065-8;
RA   Perry M., Thomsen G.H., Roeder R.G.;
RT   "Genomic organization and nucleotide sequence of two distinct histone gene
RT   clusters from Xenopus laevis. Identification of novel conserved upstream
RT   sequence elements.";
RL   J. Mol. Biol. 185:479-499(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Perry M., Thomsen G.H., Roeder R.G.;
RT   "Genomic organization and nucleotide sequence of two distinct histone gene
RT   clusters from Xenopus laevis: identification of novel conserved upstream
RT   sequence elements.";
RL   J. Biol. Chem. 260:479-499(1985).
CC   -!- FUNCTION: Histones H1 are necessary for the condensation of nucleosome
CC       chains into higher-order structures.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Chromosome.
CC   -!- SIMILARITY: Belongs to the histone H1/H5 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00837}.
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DR   EMBL; X03017; CAA26812.1; -; Genomic_DNA.
DR   EMBL; M21286; AAA49764.1; -; Genomic_DNA.
DR   PIR; D24510; HSXL1B.
DR   PIR; I51447; I51447.
DR   RefSeq; XP_018118224.1; XM_018262735.1.
DR   AlphaFoldDB; P06893; -.
DR   SMR; P06893; -.
DR   GeneID; 108716538; -.
DR   KEGG; xla:108716538; -.
DR   OMA; QFKIAKF; -.
DR   OrthoDB; 1565299at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 108716538; Expressed in oocyte and 7 other tissues.
DR   GO; GO:0000786; C:nucleosome; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006334; P:nucleosome assembly; IEA:InterPro.
DR   CDD; cd00073; H15; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005819; H1/H5.
DR   InterPro; IPR005818; Histone_H1/H5_H15.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00538; Linker_histone; 1.
DR   PRINTS; PR00624; HISTONEH5.
DR   SMART; SM00526; H15; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51504; H15; 1.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000305"
FT   CHAIN           2..220
FT                   /note="Histone H1B"
FT                   /id="PRO_0000195934"
FT   DOMAIN          40..113
FT                   /note="H15"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00837"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          99..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..220
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   220 AA;  22440 MW;  65406D359D201F03 CRC64;
     MTATTETAPV APPAEPAAAK KTKKQQPKKV AGGAKAKKPS GPSASELIVK AVSSSKERSG
     VSLAALKKAL AAGGYDVDKN NSRLKLALKA LVTKGTLTQV KGSGASGSFK LNKKQLETKD
     KAAKKKPAAP KAKKTAAGAK KAPKSPKKPK KVSAAAKSPK KVKKLAKAAK SPKKPKAVKA
     KKVAKSPAKK ATKPKTAKSP AKAKVAKPKA AKAKKPAPKK